Cardiovascular medicine

Temporal trends and patient determinants of geographical variation in oral anticoagulant treatment of atrial fibrillation: a Danish nationwide cohort study in 2013–2022
Ina Grønkjær Laugesen, Anders Prior, Flemming Bro, Anna Mygind, Erik Lerkevang Grove

BMJ Open May 2025, 15 (5) e098129; DOI: 10.1136/bmjopen-2024-098129
Rationale and design of ‘discontinuing statins in multimorbid older adults without cardiovascular disease (STREAM)’: study protocol of a randomised non-inferiority clinical trial
Philipp Stefan Aebi, Luise Adam, Moa Haller, Julia Bianca Bardoczi, Baris Gencer, Fabrice Bonnet, Jürg-Hans Beer, Sebastian Carballo, Mirjam Christ-Crain, Martin Feller, Luca Gabutti, Alan G Haynes, Elisavet Moutzouri, Patricia Orializ Chocano-Bedoya, Stefano Bassetti, Robert Escher, Martin Egger, Rosalinde K E Poortvliet, Philipp Schuetz, Sven Trelle, Maria M Wertli, Dina Zekry, Marie Méan, Drahomir Aujesky, Douglas Bauer, Manuel R Blum, Nicolas Rodondi

BMJ Open May 2025, 15 (5) e093833; DOI: 10.1136/bmjopen-2024-093833
Triple cardiovascular disease detection with an artificial intelligence-enabled stethoscope (TRICORDER): design and rationale for a decentralised, real-world cluster-randomised controlled trial and implementation study
Mihir A Kelshiker, Patrik Bächtiger, Josephine Mansell, Daniel B Kramer, Saloni Nakhare, Melanie T Almonte, Abdullah Alrumayh, Camille F Petri, Alexei Peters, Ceire Costelloe, Emanuela Falaschetti, Carys Barton, Rasha Al-Lamee, Azeem Majeed, Carla M Plymen, Nicholas S Peters

BMJ Open May 2025, 15 (5) e098030; DOI: 10.1136/bmjopen-2024-098030
Comorbid cardiovascular diseases and predictors among adults with type 2 diabetes in Bahir Dar city, Ethiopia: a multicentre hospital-based cross-sectional study
Zemenu Addis, Alemeshet Yirga Berhie, Teshager Woldegiyorgis Abate, Bekalu Mekonen Belay, Habtam Wale, Ayenew Tega, Tamiru Alene

BMJ Open May 2025, 15 (5) e086054; DOI: 10.1136/bmjopen-2024-086054
PARIS coronary thrombosis risk score combined with D-dimer to guide new oral anticoagulant antithrombotic therapy in patients with acute coronary syndrome after percutaneous coronary intervention: study protocol for the PRIDE-ACS trial
Sida Jia, Ying Song, Deshan Yuan, Peizhi Wang, Jingjing Xu, Yan Chen, Ce Zhang, Xueyan Zhao, Jin-qing Yuan

BMJ Open May 2025, 15 (5) e090126; DOI: 10.1136/bmjopen-2024-090126
Evaluating atherosclerosis prevalence via coronary calcium in executives with normal LDL levels in the US: a cohort study–the clear protocol
Basem M Ratrout, Basant E Katamesh, Ann Vincent, Ryan T Hurt, Sara Bonnes, Jayanth Adusumalli, Donna K Lawson, Darrell Schroeder, Christina D VerNess, Ivana Croghan

BMJ Open May 2025, 15 (5) e094899; DOI: 10.1136/bmjopen-2024-094899
Short- and long-term outcomes of ST-segment elevation myocardial infarction treated with CABG: a population-based cohort study
Emmi Saura, Vesa Anttila, Jarmo Gunn, Ville Kytö

BMJ Open May 2025, 15 (5) e089451; DOI: 10.1136/bmjopen-2024-089451
Tirofiban efficacy and safety for percutaneous coronary intervention in patients with acute coronary syndrome: protocol for a systematic review and meta-analysis
Daniel Andries Gigliotti, Márcia Gisele Santos da Costa, Ana Helena Silva Santos, Marcelo G Correia, Marisa Santos

BMJ Open May 2025, 15 (5) e093477; DOI: 10.1136/bmjopen-2024-093477
Sex-based outcomes of mitral surgery for ischaemic mitral regurgitation: protocol for a systematic review and meta-analysis
Kenza Rahmouni, Nicolas Mathieu Gauthier, Navneet Kang, Pierre Voisine, Jodi Edwards, Tim Ramsay, Vincent Chan

BMJ Open May 2025, 15 (5) e097759; DOI: 10.1136/bmjopen-2024-097759
Development and validation of a risk prediction model for adverse outcomes in patients with suspected coronary artery disease and no significant stenosis on angiography: a retrospective cohort study
Lei Zhu, Zheng-Kai Xue, Xue Wu, JingKun Zhang, Su-Tao Hu, Yu-Kun Zhang, Tian-Shu Gu, Tong Liu, Seung-Woon Rha, Kang-Yin Chen

BMJ Open May 2025, 15 (5) e092614; DOI: 10.1136/bmjopen-2024-092614

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