Emergency medicine

Prehospital antibiotics and intravenous fluids for patients with sepsis: protocol for a 2×2 factorial randomised controlled trial
Damon C. Scales, Anna Rogowsky, Lisa Burry, Jim Christenson, Nick Daneman, Ian R. Drennan, Morgan Hillier, Sandra Jenneson, Gail Klein, Tony Mazzulli, Philip Moran, Andrew M. Morris, Laurie J. Morrison, Ruxandra Pinto, Gordon D. Rubenfeld, Christopher W. Seymour, Rob Stenstrom, P. Richard Verbeek, Sheldon Cheskes

BMJ Open May 2025, 15 (5) e104257; DOI: 10.1136/bmjopen-2025-104257
Analgesic effects of intrathecal bupivacaine with neostigmine or morphine among elective surgical patients in selected comprehensive specialised hospitals, Southern Ethiopia: a prospective cohort study
Nesredin Shemsu Delmolo, Temesgen Sidamo, Ashagrie Sintayehu, Selman Reshad, Abdulkadir Kedir, Mebratu Kebede, Mebratu Tila, Sintayehu Samuel, Rashed Edris Usure, Nuredin Chura Waritu, Mohammed Jemal, Getahun Dendir

BMJ Open May 2025, 15 (5) e093193; DOI: 10.1136/bmjopen-2024-093193
Outcomes associated with older patients who present or develop delirium in the emergency department: protocol for a systematic review and meta-analysis
Sarah King, Oddvar Uleberg, Sindre A Pedersen, Lars Petter Bjørnsen

BMJ Open May 2025, 15 (5) e095495; DOI: 10.1136/bmjopen-2024-095495
Incidence, causes and prognostic outcomes of acute coma: a nationwide population-based retrospective cohort study in Taiwan
Chih-Yuan Lin, Chih-Ching Liu, Jen-Feng Liang, Mingche Tsai, Yue-Chune Lee, Meng-Ling Chang

BMJ Open May 2025, 15 (5) e086789; DOI: 10.1136/bmjopen-2024-086789
Contrasting cultures of emergency department care: a qualitative study of patients’ experiences of attending the emergency department for low back pain in the UK
Clare Ryan, Catherine Pope, Lisa C Roberts

BMJ Open May 2025, 15 (5) e091158; DOI: 10.1136/bmjopen-2024-091158
Impact of early haemodynamic assessment by echocardiography on organ dysfunction and outcome of patients admitted to the emergency department with sepsis or septic shock: protocol of a multicentre randomised controlled trial (GENESIS)
Thomas Lafon, Amélie Le Gouge, Samia Brit, Bruno Giraudeau, Philippe Vignon

BMJ Open May 2025, 15 (5) e098304; DOI: 10.1136/bmjopen-2024-098304
Point-of-care troponin tests to rule out acute myocardial infarction in the prehospital environment: a protocol for a systematic review and meta-analysis
Bader Albaqami, Jacqueline Dinnes, Theresa HM Moore, Kim Kirby, Simon D Carley, Mohammad Aloufi, Naif Alqurashi, Abdulrhman Alghamdi, Sara Alsuwais, Sarah Dawson, Richard Body

BMJ Open May 2025, 15 (5) e094390; DOI: 10.1136/bmjopen-2024-094390
Prospective observational study to assess the performance accuracy of clinical decision rules in children presenting to emergency departments with possible cervical spine injuries: the Study of Neck Injuries in Children (SONIC)
Natalie Phillips, Geoffrey N Askin, Gavin A Davis, Sharon O’Brien, Meredith L Borland, Amanda Williams, Amit Kochar, Blessy John-Denny, Sarah Watson, Shane George, Michelle Davison, Stuart Dalziel, Eunicia Tan, Shu-Ling Chong, Simon Craig, Arjun Rao, Susan M Donath, Chris J Selman, Stacy Goergen, Catherine L Wilson, Sonia Singh, Nathan Kuppermann, Julie C Leonard, Franz E Babl

BMJ Open May 2025, 15 (5) e096294; DOI: 10.1136/bmjopen-2024-096294
Is ambulance conveyance associated with distance to hospital and patient outcomes? A register-based cohort study in Region Zealand, Denmark, 2017–2022
Josefine Tangen Jensen, Thea Palsgaard Møller, Signe Amalie Wolthers, Stig Nikolaj Fasmer Blomberg, Annette Ersbøll, Helle Collatz Christensen

BMJ Open Apr 2025, 15 (4) e097283; DOI: 10.1136/bmjopen-2024-097283
Effectiveness of concussion treatments in older adults: a systematic review protocol
Franciely Daiana Engel, Stephen G Fung, Aurelie Tonjock Fonka, Rosie Papp, Ashley Lam, Lindsey Sikora, Sharon Johnston, Roger Zemek, Wenshan Li, Stacey Fisher, Peter Tanuseputro, Chantal Backman

BMJ Open Apr 2025, 15 (4) e096967; DOI: 10.1136/bmjopen-2024-096967

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