Post-Acute COVID-19 Syndrome

Cohort profile: characterisation, determinants, mechanisms and consequences of the long-term effects of COVID-19 – providing the evidence base for health care services (CONVALESCENCE) in the UK
Alexandra Jamieson, Lamia Al Saikhan, Betty Raman, Lamis Alghamdi, Nathan J Cheetham, Pauline Conde, Richard Dobson, Alba Fernández-Sanlés, Amos Folarin, Lucy J Goudswaard, Lee Hamill Howes, Siana Jones, Stefan Neubauer, Michele Orini, Iain Pierce, Yatharth Ranjan, Alicja Rapala, Stephen M Smith, Carole Sudre, Ellen J Thompson, James Wild, Dylan Williams, Andrew Wong, Claire J Steves, Nic Timpson, Nishi Chaturvedi, Alun Hughes

BMJ Open Jun 2025, 15 (6) e094760; DOI: 10.1136/bmjopen-2024-094760
Estimating the prevalence of persistent symptoms after SARS-CoV-2 infection (post-COVID-19 syndrome): a regional cross-sectional study protocol
Lindybeth Sarmiento Varón, Hermy Alvarez, Leyla Carolina Huirimilla Casanova, Maria Paz Díaz Mora, Luis Alfredo Muñoz Cuevas, Jorge Gonzalez-Puelma, Karena Espinoza, Lidia Amarales, Jonathan Lühr Henriquez, Felipe Retamal-Matus, Roberto Uribe-Paredes, Cristian Andrés Núñez-Espinosa, Claudia Estrada-Goic, Vivienne C Bachelet, Mercedes N López Nitsche, Marcelo A Navarrete

BMJ Open May 2025, 15 (5) e093844; DOI: 10.1136/bmjopen-2024-093844
Ashwagandha (Withania somnifera (L.) Dunal) for promoting recovery in long covid: protocol for a randomised placebo-controlled clinical trial (APRIL Trial)
Poppy Alice Carson Mallinson, Manisha Joshi, Mahesh Mathpathi, Alexander Perkins, Tim Clayton, Anoop SV Shah, Rohini Mathur, Nick Birk, Arandeep Dhillon, Judith Lieber, Sidra S Beg, Lily Hopkins, Archie Khan, Shereen Allaham, Vanessa TW Kam, Shailen Sutaria, Galib R, S Rajagopala, Amarjeet Bhamra, Geetha Krishnan G Pillai, Kamlesh Khunti, Tanuja Nesari, Sanjay Kinra

BMJ Open Apr 2025, 15 (4) e094526; DOI: 10.1136/bmjopen-2024-094526
STatin TReatment for COVID-19 to Optimise NeuroloGical recovERy (STRONGER): study protocol for a randomised, open label clinical trial in patients with persistent neurological symptoms after COVID-19 infection
Carlos Delfino, Cheryl Carcel, Xiaolei Lin, Paula Muñoz-Venturelli, Sharon L Naismith, Mark Woodward, Ruth Peters, Nirupama Wijesuriya, Meng Law, Ian H Harding, Xia Wang, Julian Elliott, Karin Leder, Owen Hutchings, Ximena Stecher, Sophia Zoungas, Craig S Anderson

BMJ Open Apr 2025, 15 (4) e089382; DOI: 10.1136/bmjopen-2024-089382
Ten sessions of hyperbaric oxygen versus sham treatment in patients with long covid (HOT-LoCO): a randomised, placebo-controlled, double-blind, phase II trial
Anders Kjellberg, Adrian Hassler, Emil Boström, Sara El Gharbi, Sarah Al-Ezerjawi, Anna Schening, Katarina Fischer, Jan H Kowalski, Kenny A Rodriguez-Wallberg, Judith Bruchfeld, Marcus Ståhlberg, Malin Nygren-Bonnier, Michael Runold, Peter Lindholm

BMJ Open Apr 2025, 15 (4) e094386; DOI: 10.1136/bmjopen-2024-094386
Effectiveness and tolerance of exercise interventions for long COVID: a systematic review of randomised controlled trials
Cillian P McDowell, Barrie Tyner, Shibu Shrestha, Leah McManus, Fearghal Comaskey, Patricia Harrington, Kieran A Walsh, Michelle O’Neill, Mairin Ryan

BMJ Open Mar 2025, 15 (3) e082441; DOI: 10.1136/bmjopen-2023-082441
Assessing the impact of COmorbidities and Sociodemographic factors on Multiorgan Injury following COVID-19: rationale and protocol design of COSMIC, a UK multicentre observational study of COVID-negative controls
Simran Shergill, Mohamed Elshibly, Sandeep S Hothi, Kelly S Parke, Rachel J England, Joanne V Wormleighton, George J Hudson, Elizabeth M Tunnicliffe, James Wild, Stephen M Smith, Sue Francis, Mark Toshner, Naveed Sattar, Kamlesh Khunti, Christopher E Brightling, Charalambos Antoniades, Colin Berry, John P Greenwood, Alastair Moss, Stefan Neubauer, Gerry P McCann, Betty Raman, Jayanth Ranjit Arnold

BMJ Open Mar 2025, 15 (3) e089508; DOI: 10.1136/bmjopen-2024-089508
Characteristics of patients with COVID-19 and smell and/or taste disorders depending on different virus strains: a cross-sectional study in Hiroshima, Japan
Yumeka Ota, Yui Yumiya, Odgerel Chimed-Ochir, Aya Hasegawa, Takahito Yoshida, Tatsuhiro Nagata, Junko Tanaka, Hiroki Ohge, Masao Kuwabara, Tatsuhiko Kubo

BMJ Open Feb 2025, 15 (2) e088377; DOI: 10.1136/bmjopen-2024-088377
Cluster analysis of post-COVID-19 physical and mental health outcomes 3–6 months after SARS-CoV-2 infection: results of the French Prospective ALCOVID Cohort Study
Thomas Escoda, Laurent Chiche, Hervé Faralli, Frédéric Cohen, Philippe Halfon, Hervé Pegliasco, Stanislas Rebaudet

BMJ Open Feb 2025, 15 (2) e089136; DOI: 10.1136/bmjopen-2024-089136
Energy management education for persons living with long COVID-related fatigue (EMERGE): protocol of a two-parallel arms target trial emulation study in a multicentre outpatient intervention setting with an online control group register
Ruth Hersche, Andrea Weise, Emilia Riggi, Gian Luca Di Tanna, Marco Barbero

BMJ Open Feb 2025, 15 (2) e098574; DOI: 10.1136/bmjopen-2024-098574

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