Gastrointestinal tumours

Clinical study of adebrelimab in combination with apatinib and irinotecan for PD-1 inhibitor-ineffective advanced-stage gastric cancer: study protocol for a single-arm, single-centre, exploratory trial
Tao Liu, Yujing Guan, Long Bai, Bo Ni, Hao-yu Zhang, Yeqian Zhang, Jiayi Gu, Muerzhate Aimaiti, Shuchang Wang, Ben Yue, Zizhen Zhang, Xiang Xia

BMJ Open Jun 2025, 15 (6) e089286; DOI: 10.1136/bmjopen-2024-089286
Impact of race, sex and age on the probability of pancreatic cancer among patients with newly diagnosed diabetes in a claims-based cohort
Elham Afghani, Bryan Lau, Laura K Becker, Michael Goggins, Alison P Klein

BMJ Open May 2025, 15 (5) e099488; DOI: 10.1136/bmjopen-2025-099488
Does paired genetic testing improve targeted therapy choices and screening recommendations for patients with upper gastrointestinal cancers and their families? A prospective cohort of 42 patients
Kevin Tatunay, Stacey Cohen, Lorraine V Naylor, Cynthia L Handford, Angela Jacobson, Veena Shankaran, Brant Oelschlager, William M Grady, Britta Sjoding, Everett Lally, Lauren Facchini, Qin Sun, Mercy Y Laurino, Colin Pritchard, Eric Q Konnick, Marianne E Dubard-Gault

BMJ Open May 2025, 15 (5) e091745; DOI: 10.1136/bmjopen-2024-091745
Risk factors for neuroendocrine neoplasms: protocol for a case–control study based on a record linkage of registry and claims data
Sven Voigtländer, Roman Gerlach, Nina Grundmann, Ewan Donnachie, Ursula Berger, Amir Hakimhashemi, Martin Meyer, Martin Tauscher, Jacqueline Müller-Nordhorn

BMJ Open May 2025, 15 (5) e096273; DOI: 10.1136/bmjopen-2024-096273
Sociodemographic factors associated with psychosocial consequences of false-positive colorectal cancer screening: a prospective cohort study
Emma Grundtvig Gram, Jessica á Rogvi, Volkert Siersma, Dagny Ros Nicolaisdottir, John Brandt Brodersen

BMJ Open May 2025, 15 (5) e090967; DOI: 10.1136/bmjopen-2024-090967
A phase I, open-label, multicentre, first-in-human study to evaluate safety, pharmacokinetics and efficacy of AMG 404, a PD-1 inhibitor, in patients with advanced solid tumours
Timothy Price, Iwona Lugowska, Sant P Chawla, Gerald Falchook, Vivek Subbiah, Jose G Monzon, Hendrik-Tobias Arkenau, Mun Hui, Yasutoshi Kuboki, Rafal Dziadziuszko, Ryota Shibaki, Min Hee Hong, Daniel Tan, Caio Max Rocha Lima, Kejia Wang, Antreas Hindoyan, Weibing Shi, Hansen Wong, Mira Kistler, Hans Prenen

BMJ Open May 2025, 15 (5) e088578; DOI: 10.1136/bmjopen-2024-088578
Optimising colorectal cancer screening strategies and target populations in budget-constrained regions through cost-effectiveness analysis: a case from eastern China
Hao Li, Yun Fu, Ao Xu, Peng Zhang, Weibing Wang

BMJ Open May 2025, 15 (5) e087216; DOI: 10.1136/bmjopen-2024-087216
Contact radiotherapy for rectal cancer (CORRECT): study protocol for a multicentre randomised phase II trial
Per J Nilsson, Joakim Folkesson, Richard Marsk, Calin Radu, Iuliana Stratulat, Lennart Blomqvist, Anna Martling, Alexander Valdman

BMJ Open Apr 2025, 15 (4) e100356; DOI: 10.1136/bmjopen-2025-100356
Clinical prediction tools for patient-reported outcomes in gastrointestinal cancer: a scoping review protocol
Alice Zhu, Ka Yan Ip, Alyson Mahar, Amy T Hsu, Paul D James, Ekaterina Kosyachkova, Teresa Tiano, Julie Hallet, Natalie G Coburn

BMJ Open Mar 2025, 15 (3) e097966; DOI: 10.1136/bmjopen-2024-097966
Machine learning models for prediction of lymph node metastasis in patients with gastric cancer: a Chinese single-centre study with external validation in an Asian American population
Qian Li, Shangcheng Yan, Weiran Yang, Zhuan Du, Ming Cheng, Renwei Chen, Qiankun Shao, Yuan Tian, Mengchao Sheng, Wei Peng, Yongyou Wu

BMJ Open Mar 2025, 15 (3) e098476; DOI: 10.1136/bmjopen-2024-098476

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