hemodynamics/physiology

Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usual care in patients undergoing major elective gastrointestinal surgery
Mark R Edwards, Gordon Forbes, Neil MacDonald, Vladislav Berdunov, Borislava Mihaylova, Priyanthi Dias, Ann Thomson, Michael PW Grocott, Monty G Mythen, Mike A Gillies, Michael Sander, Tuong D Phan, Lisbeth Evered, Duminda N Wijeysundera, Stuart A McCluskey, Cesar Aldecoa, Javier Ripollés-Melchor, Christoph K Hofer, Hussein Abukhudair, Wojciech Szczeklik, Ioana Grigoras, Ludhmila A Hajjar, Brennan C Kahan, Rupert M Pearse

BMJ Open Jan 2019, 9 (1) e023455; DOI: 10.1136/bmjopen-2018-023455

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hemodynamics/physiology