Haematology (incl blood transfusion)

Designing a single-arm phase 2 clinical trial of mitapivat for adult patients with erythrocyte membranopathies (SATISFY): a framework for interventional trials in rare anaemias – pilot study protocol
Andreas Glenthøj, Eduard J van Beers, Richard van Wijk, Minke A E Rab, Evelyn Groot, Niels Vejlstrup, Nina Toft, Selma Kofoed Bendtsen, Jesper Petersen, Jens Helby, Fatiha Chermat, Pierre Fenaux, Kevin H M Kuo

BMJ Open Jul 2024, 14 (7) e083691; DOI: 10.1136/bmjopen-2023-083691
Phase II study in children and adults under 40 years with newly diagnosed Langerhans cell histiocytosis: protocol for an LCH-19-MSMFB clinical trial in Japan
Rintaro Ono, Kenichi Sakamoto, Ko Kudo, Aki Sato, Kazuko Kudo, Hisanori Fujino, Yuta Kawahara, Hiroya Hashimoto, Takehiko Doi, Ryu Yanagisawa, Toyotaka Kawamata, Osamu Miyazaki, Atsuko Nakazawa, Yasunori Ota, Hirokazu Kanegane, Yozo Nakazawa, Keizo Horibe, Akiko M Saito, Atsushi Manabe, Kensuke Usuki, Hitoshi Kiyoi, Akira Morimoto, Arinobu Tojo, Yoko Shioda

BMJ Open Jun 2024, 14 (6) e084159; DOI: 10.1136/bmjopen-2024-084159
Flow cytometric analysis of peripheral blood neutrophil myeloperoxidase expression in myelodysplastic neoplasms (MPO-MDS-Valid): protocol for a multicentre diagnostic accuracy study
Charlotte Planta, Caroline Bret, Delphine Manzoni, Anne-Catherine Lhoumeau, Caroline Mayeur Rousse, Michel Ticchioni, Lydia Campos, Alice Eischen, Nicolas Gonnet, Raymond Merle, Arnaud Seigneurin, Franciane Paul, Estelle Comte, Alessandra Allieri-Rosenthal, Sylvie Tondeur, Chloé Regnart, Marie-Christine Jacob, José Labarère, Sophie Park, Tatiana Raskovalova

BMJ Open Jun 2024, 14 (6) e081200; DOI: 10.1136/bmjopen-2023-081200
Compassionate Communication and Advance Care Planning to improve End-of-life Care in Treatment of Haematological Disease ‘ACT’: Study Protocol for a Cluster-randomized trial
Cæcilie Borregaard Myrhøj, Stine Novrup Clemmensen, Mary Jarden, Christoffer Johansen, Annika von Heymann

BMJ Open May 2024, 14 (5) e085163; DOI: 10.1136/bmjopen-2024-085163
Web-based cognitive rehabilitation intervention for cancer-related cognitive impairment following chemotherapy for aggressive lymphoma: protocol for a randomised pilot trial
Priscilla Gates, Heather J Green, Karla Gough, Haryana Dhillon, Janette L Vardy, Michael Dickinson, Jade Guarnera, Meinir Krishnasamy, Patricia M Livingston, Victoria White, Anna Ugalde, Karen Caeyenberghs

BMJ Open Apr 2024, 14 (4) e081084; DOI: 10.1136/bmjopen-2023-081084
Protocol for a mixed-methods study to develop and feasibility test a digital system for the capture of patient-reported outcomes (PROs) in patients receiving chimeric antigen receptor T-cell (CAR-T) therapies (the PRO-CAR-T study)
Sarah E Hughes, Christel McMullan, Olalekan Lee Aiyegbusi, Karen Shaw, Francesca Kinsella, Paul Ferguson, Foram Khatsuria, David Burns, Lester Pyatt, John Ansell, Evelyn Chakera, Julie Richardson-Abraham, Alastair K Denniston, Elin Haf Davies, Charles Craddock, Melanie Calvert

BMJ Open Mar 2024, 14 (3) e085392; DOI: 10.1136/bmjopen-2024-085392
Rituximab-combined anthracycline-free chemotherapy in newly diagnosed paediatric and adolescent patients with non-high-risk aggressive mature B cell lymphoma: protocol for a single-arm, open-label, multicentre, phase II study (the Japan Children’s Cancer Group Multicentre Trial, JPLSG B-NHL-20)
Masahiro Sekimizu, Reiji Fukano, Yuhki Koga, Tetsuo Mitsui, Naoto Fujita, Takeshi Mori, Daiki Hori, Makito Tanaka, Kentaro Ohki, Hideto Iwafuchi, Atsuko Nakazawa, Tetsuya Mori, Ryoji Kobayashi, Hiroya Hashimoto, Akiko M. Saito, Michi Kamei

BMJ Open Mar 2024, 14 (3) e080762; DOI: 10.1136/bmjopen-2023-080762
Prognostic and clinicopathological significance of the Controlling Nutritional Status (CONUT) score in patients with lymphoma: a meta-analysis
Lili Li, Lihong Shou

BMJ Open Mar 2024, 14 (3) e078320; DOI: 10.1136/bmjopen-2023-078320
Self-management needs, strategies and support for sickle cell disease in developing countries: a scoping review protocol
Andrews Adjei Druye, Christian Makafui Boso, Mustapha Amoadu, Paul Obeng, Bernard Nabe, Justice Enock Kagbo, Patience Fakornam Doe, Christiana Okantey, Godson Obeng Ofori, Rita Opoku-Danso, Dorcas Frempomaa Agyare, Gifty Osei Berchie, Gifty Owusu, Frederick Nsatimba, Susanna Aba Abraham

BMJ Open Mar 2024, 14 (3) e083688; DOI: 10.1136/bmjopen-2023-083688
Efficacy and safety of deferoxamine, deferasirox and deferiprone triple iron chelator combination therapy for transfusion-dependent β-thalassaemia with very high iron overload: a protocol for randomised controlled clinical trial
Anuja Premawardhena, Chamodi Perera, Muditha Nayana Wijethilaka, Sakuni Keshani Wanasinghe, R H M G Rajakaruna, R A N K K Samarasinghe, Senani Williams, Sachith Mettananda

BMJ Open Feb 2024, 14 (2) e077342; DOI: 10.1136/bmjopen-2023-077342

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