TRANSCENDENT (Transforming Research by Assessing Neuroinformatics across the Spectrum of Concussion by Embedding iNterdisciplinary Data-collection to Enable Novel Treatments): protocol for a prospective observational cohort study of concussion patients with embedded comparative effectiveness research within a network of learning health system concussion clinics in CanadaRoger Zemek, Lisa M Albrecht, Sharon Johnston, John Leddy, Andrée-Anne Ledoux, Nick Reed, Noah Silverberg, Keith Yeates, Monica Lamoureux, Charlotte Anderson, Nicholas Barrowman, Miriam H Beauchamp, Kitty Chen, Araba Chintoh, Achelle Cortel-LeBlancSee the full list of authors
22 April 2025
STatin TReatment for COVID-19 to Optimise NeuroloGical recovERy (STRONGER): study protocol for a randomised, open label clinical trial in patients with persistent neurological symptoms after COVID-19 infectionCarlos Delfino, Cheryl Carcel, Xiaolei Lin, Paula Muñoz-Venturelli, Sharon L Naismith, Mark Woodward, Ruth Peters, Nirupama Wijesuriya, Meng Law, Ian H Harding, Xia Wang, Julian Elliott, Karin Leder, Owen Hutchings, Ximena StecherSee the full list of authors
14 April 2025
Efficacy of deep brain stimulation in treating monogenic dystonia symptoms: protocol for a systematic reviewBeatriz Carmona-Hidalgo, Javier Quintero, Rocío Rodríguez-López, Juan Antonio Blasco-Amaro, Sylvia Boesch, Carola Reinhard
9 April 2025
Prognostic factors of disability progression in multiple sclerosis in real life: the OFSEP-high definition (OFSEP-HD) prospective cohort in FranceGuillemin Francis, Casey Romain, Epstein Jonathan, Foucher Yohann, Laplaud David, Achit Hamza, Rollot Fabien, Leray Emmanuelle, Vukusic Sandra, , OFSEP-HD investigators, Eric BERGER, Pierre BRANGER, Philippe CABRE, Olivier CASEZSee the full list of authors
7 April 2025
Personalised selection of medication for newly diagnosed adult epilepsy: study protocol of a first-in-class, double-blind, randomised controlled trialDaniel Thom, Richard Shek-kwan Chang, Natasha A Lannin, Zanfina Ademi, Zongyuan Ge, David Reutens, Terence O’Brien, Wendyl D’Souza, Piero Perucca, Sandra Reeder, Armin Nikpour, Chong Wong, Michelle Kiley, Jacqui-Lyn Saw, John-Paul NicoloSee the full list of authors
5 April 2025
Longitudinal dynamics of pulse wave velocity in the days after acute ischaemic stroke: prospective cohort studyKurt Moelgg, Anel Karisik, Benjamin Dejakum, Silvia Felicetti, Christian Boehme, Lukas Mayer-Suess, Thomas Toell, Michael Knoflach, Stefan Kiechl, Raimund Pechlaner
3 April 2025
TRanscutaneous lImb reCovEry Post-Stroke (TRICEPS): study protocol for a randomised, controlled, multiarm, multistage adaptive design trialSheharyar S Baig, Cara Mooney, Kirsty McKendrick, Kate E M Duffy, Ali N Ali, Jessica N Redgrave, Esther Herbert, Simon Waterhouse, Li Su, Avril Drummond, Jesse Dawson, Munyaradzi Dimairo, Katie Biggs, Cindy Cooper, Arshad Majid
26 March 2025
Effects of poststroke heart rate variability on the neurological impairment severity and the prognosis among patients with ischaemic stroke: a scoping reviewRuiying Zhang, Jianan Hong, Xiaoting Zheng, Shuying Chen, Liling Lin, Yingxiu Xiao
24 March 2025
Role of inflammation and haemostasis on aetiology and prognosis in young patients with ischaemic stroke: study protocol of the Observational Dutch Young Symptomatic StrokE study—EXTended (ODYSSEY-nEXT) – a multicentre prospective cohort studyJanneke P Spiegelenberg, Esmée Verburgt, Heleen den Hertog, Karlijn F de Laat, Frank G van Rooij, Inge W M van Uden, Renate M Arntz, Ido R van den Wijngaard, Roy P C Kessels, Vitória Piai, Anja van der Kolk, Mark Roest, Bas de Laat, Saskia Middeldorp, Anil TuladharSee the full list of authors
21 March 2025
Impact of stroke severity on aspiration pneumonia risks in the medical ward versus the stroke unit: a 10-year retrospective cohort studyKim H Tran, Naveed Akhtar, Aizaz Ali, Sujata Joseph, Deborah Morgan, Blessy Babu, Ryan Ty Uy, Ashfaq Shuaib
21 March 2025