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The older the better: are elderly study participants more non-representative? A cross-sectional analysis of clinical trial and observational study samples

Authors

  • Beatrice A Golomb Department of Medicine, University of California, San Diego, California, USA Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California, USA PubMed articlesGoogle scholar articles
  • Virginia T Chan Department of Medicine, University of California, San Diego, California, USA University of California, Irvine School of Medicine, Irvine, California, USA PubMed articlesGoogle scholar articles
  • Marcella A Evans Department of Medicine, University of California, San Diego, California, USA University of California, Irvine School of Medicine, Irvine, California, USA PubMed articlesGoogle scholar articles
  • Sabrina Koperski Department of Medicine, University of California, San Diego, California, USA PubMed articlesGoogle scholar articles
  • Halbert L White Department of Economics, University of California, San Diego, La Jolla, California, USA PubMed articlesGoogle scholar articles
  • Michael H Criqui Department of Medicine, University of California, San Diego, California, USA Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Beatrice A Golomb; bgolomb{at}ucsd.edu
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Citation

Golomb BA, Chan VT, Evans MA, et al
The older the better: are elderly study participants more non-representative? A cross-sectional analysis of clinical trial and observational study samples
BMJ Open 2012;2:e000833. doi: 10.1136/bmjopen-2012-000833

Publication history

  • Received July 27, 2012
  • Revised October 16, 2012
  • Accepted November 5, 2012
  • First published December 14, 2012.
Online issue publication 
October 25, 2017
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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com.ezproxy.u-pec.fr/group/rights-licensing/permissions This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/2.0/ and http://creativecommons.org/licenses/by-nc/2.0/legalcode.