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Comparing biparametric to multiparametric MRI in the diagnosis of clinically significant prostate cancer in biopsy-naive men (PRIME): a prospective, international, multicentre, non-inferiority within-patient, diagnostic yield trial protocol

Authors

  • Aqua Asif Division of Surgery and Interventional Science, University College London, London, UK PubMed articlesGoogle scholar articles
  • Arjun Nathan Division of Surgery and Interventional Science, University College London, London, UKClinical Effectiveness Unit, Royal College of Surgeons of England, London, UK PubMed articlesGoogle scholar articles
  • Alexander Ng Division of Surgery and Interventional Science, University College London, London, UK PubMed articlesGoogle scholar articles
  • Pramit Khetrapal Division of Surgery and Interventional Science, University College London, London, UKDepartment of Urology, Whipps Cross University Hospital, London, UK PubMed articlesGoogle scholar articles
  • Vinson Wai-Shun Chan Division of Surgery and Interventional Science, University College London, London, UK PubMed articlesGoogle scholar articles
  • Francesco Giganti Division of Surgery and Interventional Science, University College London, London, UKDepartment of Radiology, University College London Hospitals NHS Foundation Trust, London, UK PubMed articlesGoogle scholar articles
  • Clare Allen Division of Surgery and Interventional Science, University College London, London, UKDepartment of Radiology, University College London Hospitals NHS Foundation Trust, London, UK PubMed articlesGoogle scholar articles
  • Alex Freeman Department of Histopathology, University College London Hospitals NHS Foundation Trust, London, UK PubMed articlesGoogle scholar articles
  • Shonit Punwani Department of Radiology, University College London Hospitals NHS Foundation Trust, London, UKCentre for Medical Imaging, University College London, London, UK PubMed articlesGoogle scholar articles
  • Paula Lorgelly Institute of Epidemiology and Health Care, University College London, London, UKSchool of Population Health, The University of Auckland, Auckland, New Zealand PubMed articlesGoogle scholar articles
  • Caroline S Clarke Research Department of Primary Care and Population Health, University College London, London, UK PubMed articlesGoogle scholar articles
  • Chris Brew-Graves National Cancer Imaging Translational Accelerator, University College London, London, UK PubMed articlesGoogle scholar articles
  • Nicola Muirhead National Cancer Imaging Translational Accelerator, University College London, London, UK PubMed articlesGoogle scholar articles
  • Mark Emberton Division of Surgery and Interventional Science, University College London, London, UKDepartment of Urology, University College London Hospitals NHS Foundation Trust, London, UK PubMed articlesGoogle scholar articles
  • Ridhi Agarwal Test Evaluation Research Group, Institute of Applied Health Research, University of Birmingham, Birmingham, UKNIHR Birmingham Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK PubMed articlesGoogle scholar articles
  • Yemisi Takwoingi Test Evaluation Research Group, Institute of Applied Health Research, University of Birmingham, Birmingham, UKNIHR Birmingham Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK PubMed articlesGoogle scholar articles
  • Jonathan J Deeks Test Evaluation Research Group, Institute of Applied Health Research, University of Birmingham, Birmingham, UKNIHR Birmingham Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK PubMed articlesGoogle scholar articles
  • Caroline M Moore Division of Surgery and Interventional Science, University College London, London, UKDepartment of Urology, University College London Hospitals NHS Foundation Trust, London, UK PubMed articlesGoogle scholar articles
  • Veeru Kasivisvanathan Division of Surgery and Interventional Science, University College London, London, UKDepartment of Urology, University College London Hospitals NHS Foundation Trust, London, UK PubMed articlesGoogle scholar articles
  • PRIME Trial Group
    Google scholar articles
  1. Correspondence to Veeru Kasivisvanathan; veeru.kasi{at}ucl.ac.uk
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Citation

Asif A, Nathan A, Ng A, et al
Comparing biparametric to multiparametric MRI in the diagnosis of clinically significant prostate cancer in biopsy-naive men (PRIME): a prospective, international, multicentre, non-inferiority within-patient, diagnostic yield trial protocol

Publication history

  • Received November 19, 2022
  • Accepted February 10, 2023
  • First published April 5, 2023.
Online issue publication 
April 05, 2023

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