Table 1

Per allele percentage increases in measures of regional adiposity (BMI, weigh, waist circumference, hip circumference, waist-hip ratio) among never, ex and current smokers, before and after adjustment for BMI

Adjusted for ageAdjusted for age and BMIp For interaction*
BMI (kg/m2)Never-smokersFormer smokersCurrent smokersp For interaction*Never-smokersFormer smokersCurrent smokers
 % increase0.35−0.14−0.74
 95% CI(0.18 to 0.52)(−0.34 to 0.07)(−0.96 to −0.51)
 p6.38×10−50.192.00×10−104.95×10−13
 N66 80943 00938 912
 I214%0%0%
Waist circumference (cm)
 % increase0.23−0.07−0.400.010.060.14
 95% CI(0.09 to 0.36)(−0.24 to 0.09)(−0.57 to −0.22)(−0.06 to 0.08)(−0.02 to 0.15)(0.05 to 0.22)
 p0.00120.371.69×10−53.85×10−70.720.150.0030.087
 N64 26540 75637 360
 I214%0%10%0%0%13%
Hip circumference (cm)
 % increase0.17−0.07−0.310.020.020.02
 95% CI(0.08 to 0.26)(−0.17 to 0.04)(−0.42 to −0.19)(−0.03 to 0.07)(−0.04 to 0.08)(−0.05 to 0.08)
 p2.95×10−40.232.55×10−71.79×10−90.380.540.590.99
 N62 32340 51236 833
 I27%0%0%16%0%0%
Waist-hip ratio
 % increase0.070−0.08−0.010.040.1
 95% CI(−0.01 to 0.15)(−0.10 to 0.10)(−0.19 to 0.03)(−0.08 to 0.06)(−0.04 to 0.13)(0.02 to 0.19)
 p0.0870.970.140.0830.780.300.020.13
 N62 32240 51236 833
 I221%9%15%0%0%13%
  • *Interaction assessed by assessing heterogeneity between effect estimates according to smoking status, with a fixed effects model.

  • BMI, body mass index.