Performance characteristics of RPR tests for diagnosis of syphilis
| Non-treponemal tests | TPPA | ||
|---|---|---|---|
| Positive | Negative | ||
| HBI HiSens Auto RPR | Positive | 31 | 3 |
| Negative | 28 | 50 | |
| Sensitivity | 52.5% | (95% CI 39.1% to 65.7%) | |
| Specificity | 94.3% | (95% CI 84.3% to 98.8%) | |
| Positive predictive value | 91.2% | (95% CI 76.3% to 98%) | |
| Negative predictive value | 64.1% | (95% CI 52.4% to 74.7%) | |
| TPPA | |||
| Positive | Negative | ||
| BD Macro-Vue RPR card | Positive | 51 | 3 |
| Negative | 8 | 50 | |
| Sensitivity | 86.4% | (95% CI 75% to 93.9%) | |
| Specificity | 94.3% | (95% CI 84.3% to 98.8%) | |
| Positive predictive value | 94.4% | (95% CI 84.6% to 98.8%) | |
| Negative predictive value | 86.2% | (95% CI 74.6% to 93.8%) | |
RPR, rapid plasma reagin; TPPA, Treponema pallidum particle agglutination.