Categories of potential adverse drug events according to severity
| Score | Potential severity | Examples |
|---|---|---|
| 0 | Drug error without potential harm | Not applicable |
| 1 | Significant | Gastrointestinal complaints |
| Therapeutically ineffective dose according to eGFR | ||
| Mild neurological effects (e.g. motoric dysfunction) | ||
| Hepatic dysfunction | ||
| Any significant event identified by patient which does not require change in therapy | ||
| 2 | Serious | Hypoglycaemia |
| Nephrotoxicity or increased risk nephrolithiasis | ||
| Electrolyte disturbances (e.g. hyperpotassiemia) | ||
| Altered mental status due to sedation | ||
| Myopathy or rhabdomyolysis | ||
| Gastrointestinal bleed | ||
| 3 | Life threatening | Lactic acidosis |
| Cardiac arrhythmia | ||
| Decline in mental status with risk of falling | ||
| Respiratory failure requiring intubation (e.g. bronchospasms) | ||
| 4 | Fatal | Death |