Table 4

Crude and adjusted* ORs; 96% CI for adverse perinatal outcome in pregnant women with T1DM and stratified on BMI

T1DM
BMI 18.5–24.9BMI 25–29.9BMI ≥30
LGA infant
 Crude1.01.13 (0.98 to 1.32)1.14 (0.95 to 1.37)
 Adjusted1.01.18 (1.01 to 1.38)1.21 (1.00 to 1.47)
Major malformations
 Crude1.00.93 (0.63 to 1.37)1.73 (1.15 to 2.58)
 Adjusted1.00.92 (0.62 to 1.36)1.77 (1.18 to 2.65)
Pre-eclampsia
 Crude1.01.17 (0.95 to 1.45)1.45 (1.13 to 1.86)
 Adjusted1.01.21 (0.98 to 1.50)1.74 (1.35 to 2.25)
Preterm delivery
 Crude1.01.23 (1.02 to 1.47)1.25 (1.00 to 1.56)
 Adjusted1.01.22 (1.02 to 1.47)1.25 (1.00 to 1.56)
Perinatal mortality
 Crude1.01.48 (0.71 to 3.08)1.14 (0.44 to 2.98)
 Adjusted1.01.47 (0.70 to 3.03)1.08 (0.41 to 2.83)
Caesarean section
 Crude1.01.38 (1.19 to 1.60)1.69 (1.40 to 2.04)
 Adjusted1.01.37 (1.18 to 1.60)1.67 (1.38 to 2.03)
Neonatal overweight
 Crude1.01.17 (0.98 to 1.40)1.35 (1.09 to 1.67)
 Adjusted1.01.19 (0.99 to 1.42)1.36 (1.09 to 1.69)
  • Reference group: type 1 diabetic women with normal pre-pregnancy BMI.

  • * Adjusted for ethnicity, maternal age, height, parity, smoking first trimester and chronic hypertension.

  • BMI, body mass index; LGA, large for gestational age; T1DM, type 1 diabetes.