Comparison of participants with and without gout
| Characteristic | Mean±SD/per cent | ||
| No gout, N=4291 | Gout, N=228 | p Value | |
| Age in years | 36±10 | 40±9 | <0.001 |
| Proportion of men (%) | 46 | 83 | <0.001 |
| Body mass index (kg/m2) | 25±4.3 | 28±4.1 | <0.001 |
| Current alcohol use (%) | 85 | 95 | <0.001 |
| Proportion of current smokers | 63 | 72 | 0.003 |
| Current diuretic use (%) | 3.2 | 7 | <0.001 |
| Systolic blood pressure (mm Hg) | 120±15 | 133±17 | <0.001 |
| Diastolic blood pressure (mm Hg) | 78±10 | 86±10 | <0.001 |
| Fasting glucose (mg/dl) | 94±22 | 104±32 | <0.001 |
| Total cholesterol (mg/dl) | 195±39 | 213±38 | <0.001 |
| LDL cholesterol (mg//dl) | 124±35 | 138±34 | <0.001 |
| HDL cholesterol (mg/dl) | 51±15 | 45±14 | <0.001 |
| Total cholesterol/HDL cholesterol ratio | 4.2±1.6 | 5.1±1.7 | <0.001 |
| Triglycerides (mg/dl) | 91±80 | 140±98 | <0.001 |
| Serum urate (mg/dl) | 5.3±1.3 | 7.3±1.4 | <0.001 |
| Renal disease/dysfunction (%)* | 3.8 | 5.8 | 0.14 |
| Diabetes (%)* | 1.5 | 3.2 | 0.06 |
| Valvular heart disease (%)* | 7.3 | 4.4 | 0.1 |
| Current antihypertensive therapy (%)* | 2 | 8.8 | <0.001 |
↵* Valvular heart disease was defined for this study as presence of cardiac murmur at baseline. Gout was determined based on physician diagnosis and/or gout medication use. Hypertension was defined as per JNC 7 guidelines and/or use of antihypertensive medications. Diabetes was defined as per the American Diabetes Association criteria or use of anti-diabetes medications. Renal disease was assessed by study physician based on history and study laboratory examination.
HDL, high-density lipoprotein; LDL, low-density lipoprotein.