Optimal characteristics of HCV scoring using external prospective validation (N=215)
Risk factors, n | Validation with prospective data set | |
HR (95% CI) | p | |
<2 | Reference | |
3 | 1.10 (0.74 to 1.60) | 0.667 |
4 | 1.15 (0.78 to 1.65) | 0.504 |
5 | 2.17 (1.45 to 3.17) | <0.001 |
≥6 | 3.19 (2.30 to 5.51) | <0.001 |
Score cut-points | Validation with prospective data set | |
Sensitivity (%) | Specificity (%) | |
≥10 | 89 | 16 |
≥15 | 78 | 33 |
≥20 | 60 | 54 |
≥25 | 41 | 70 |
HCV, hepatitis C virus.