Functional vision tests used as clinical trial outcome measures
Name of functional vision test | Disease population | ClinicalTrials.gov identifier | Type of outcome measure |
Multi Luminance Mobility Test (MLMT) | RPE65-related Leber’s congenital amaurosis | NCT00999609 | Primary |
NR2E3 and RHO-related retinitis pigmentosa | NCT05203939 | Efficacy | |
The Functional Low-Vision Observer Rated Assessment (FLORA for Argus II prosthesis) | End-stage retinitis pigmentosa | NCT02303288; NCT03406416 | Primary; Secondary |
Low Luminance Mobility Testing (LLMT) | Retinitis pigmentosa | NCT03073733 | Secondary |
Visual Navigation Challenge (Ora-VNC) | CEP290-related Leber’s congenital amaurosis | NCT03140969; NCT03872479 | Secondary |
Multi-Luminance Y-Mobility Test (MLYMT) | Retinitis pigmentosa | NCT04945772 | Secondary |
Vision-guided mobility assessment | RPE65-related retinal dystrophy | NCT02781480 | Secondary |
Orientation and mobility for Argus II prosthesis | End-stage retinitis pigmentosa | NCT00407602 | Secondary |