Table 4

Levels of evidence for a causal effect of patient activation (PAct) on T2D-related self-management behaviours

OutcomeEvidence for PAct scoresDescription
Overall self-management scoresInconclusive
  • All the studies reporting overall self-management scores were low-quality62 67 69 73

  • Although with weak design, all four consistently reported higher overall self-management scores with higher PAct scores

    • Inconclusive evidence

DietVery limited evidence of favourable association
  • All the studies available reported a more favourable diet with higher PAct scores,20 48 49 62 73 which indicate consistent results

  • These studies measured both general diet (healthy eating)20 48 49 62 73 and specific diet (fruits, vegetables and high-fat foods).62 73

  • Only one study was large and high-quality with a moderate design49

  • All the others were low-quality.

    • Very limited evidence of favourable association between diet and higher PAct scores

Physical activityVery limited evidence of favourable association
  • All studies that investigated diet also reported higher physical activity with higher PAct scores20 62 65 72–74 with the same spread of results

  • One addition is a small, low-quality study with a weak design that showed no association.68

    • Very limited evidence of favourable association between PAct scores and physical activity

SmokingVery limited evidence of no association
  • All the studies that investigated the association between smoking and PAct scores had weak designs20 65 72–74

  • Two large high-quality studies reported no association between smoking and PAct scores.65 72

  • Two large studies, one high-quality74 and one low-quality62 showed lower levels of smoking with increased PAct scores.

    • Very limited evidence of no association between smoking and PAct scores

Alcohol consumptionInconclusive
  • Only one large high-quality study with a weak design72 reported no association between alcohol consumption and PAct scores.

    • Inconclusive evidence

Medication adherenceInconclusive
  • All the studies that investigated medication adherence had weak designs.21 48 62 71 74

  • The methods used to measure medication adherence were proportion of days covered,71 74 Morisky scale21 and the Summary of Diabetes Self-Care Activities (SDSCA) tool.48 62

  • Among the high-quality studies, two (one large and one small) reported higher medication adherence with higher PAct,21 71 whereas one large study reported no association.74

    • Inconclusive evidence

  • PAct, Patient activation; T2D, type 2 diabetes.