Table 1

Schedule of enrolment, interventions and assessments

Timepoints	Study period
	Pre-radiotherapy	Interventions: radiotherapy		Post-radiotherapy
	Baseline	1 week	2 weeks	4 weeks	6 months	12 months	18 months	2 years
Enrolment
Eligibility screening	X
Informed consent	X
Interventions
Ultra-hypofractioned regimen		X	X
Assessments
History and physical examination	X	X	X	X	X	X	X	X
Chest CT scan	X*					X		X
Mammography						X		X
Ultrasound for breast and regional nodes	X				X	X	X	X
ECG	X				X	X	X	X
Echocardiography	X				X	X	X	X
Cosmetic outcomes for breast-conserving surgery	X			X	X	X	X	X
Quality of life	X			X	X	X	X	X

Annual assessments will be conducted 2 years subsequent to the completion of radiotherapy.
*Simulation CT is acceptable.