Table 4

Anchor-based Cox proportional hazards model with an MCID derived from SGRQ and ppFVC as anchors

Total (N=155)Total deaths (n=11)Risk of death, HR (95% CI)P value
QLF changes in whole lung by SGRQ using ±5 as anchor
≥4.4%27 (18%)4 (36%)6.17 (1.63, 23.4)0.007
≥91 mL47 (31%)6 (55%)7.35 (1.98, 27.3)0.003
QLF changes in whole lung by ppFVC with ±3.4% as anchor
≥3.6%41 (27%)4 (36%)4.33 (1.14, 16.5)0.031
≥65 mL60 (39%)7 (64%)8.89 (2.13, 37.0)0.003
  • Note: The anchor-based values, marked with bold fonts, are results from table 2.

  • . MCID, minimum clinically important difference; ppFVC, percent-predicted forced vital capacity; QLF, Quantitative Lung Fibrosis score; SGRQ, St. George’s Respiratory Questionnaire.