Anchor-based Cox proportional hazards model with an MCID derived from SGRQ and ppFVC as anchors
| Total (N=155) | Total deaths (n=11) | Risk of death, HR (95% CI) | P value | |
| QLF changes in whole lung by SGRQ using ±5 as anchor | ||||
| ≥4.4% | 27 (18%) | 4 (36%) | 6.17 (1.63, 23.4) | 0.007 |
| ≥91 mL | 47 (31%) | 6 (55%) | 7.35 (1.98, 27.3) | 0.003 |
| QLF changes in whole lung by ppFVC with ±3.4% as anchor | ||||
| ≥3.6% | 41 (27%) | 4 (36%) | 4.33 (1.14, 16.5) | 0.031 |
| ≥65 mL | 60 (39%) | 7 (64%) | 8.89 (2.13, 37.0) | 0.003 |
Note: The anchor-based values, marked with bold fonts, are results from table 2.
. MCID, minimum clinically important difference; ppFVC, percent-predicted forced vital capacity; QLF, Quantitative Lung Fibrosis score; SGRQ, St. George’s Respiratory Questionnaire.