Age-standardised DALYs and mortality of Parkinson’s disease in 2021 and EAPC from 1990 to 2021 globally and in different age groups and genders
| DALYs | Mortality | |||
| ASR/100 000 (95% UI) 2021 | EAPC (95% UI) 1990–2021 | ASR/100 000 (95% UI) 2021 | EAPC (95% CI) 1990–2021 | |
| Global | 89.59 (80.69–97.5) | 0.32 (0.28–0.36) | 4.81 (4.28–5.17) | 0.18 (0.13 to 0.23) |
| Sex | ||||
| Female | 68.56 (60.9–75.76) | 0.14 (0.11–0.17) | 3.59 (3.06–3.94) | −0.01 (−0.04 to 0.03) |
| Male | 117.47 (106.15–128.88) | 0.37 (0.31–0.42) | 6.57 (5.93–7.14) | 0.21 (0.14 to 0.28) |
| Age group | ||||
| 20–24 years | 0.20 (0.17–0.24) | −0.8 (−0.85–−0.76) | 0.00 (0.00–0.00) | −1.03 (−1.09 to −0.97) |
| 25–29 years | 0.49 (0.3–0.75) | −0.09 (−0.13–−0.05) | 0.00 (0.00–0.00) | −0.50 (−0.61 to −0.4) |
| 30–34 years | 1.18 (0.74–1.78) | −0.01 (−0.05–0.03) | 0.01 (0.01–0.01) | −0.67 (−0.82 to −0.53) |
| 35–39 years | 2.44 (1.6–3.56) | 0.28 (0.25–0.3) | 0.01 (0.01–0.01) | −0.54 (−0.64 to −0.45) |
| 40–44 years | 10.58 (8.7–12.92) | 0.02 (−0.03–0.06) | 0.14 (0.12–0.16) | −0.39 (−0.46 to −0.33) |
| 45–49 years | 21.64 (18.21–26.16) | 0.22 (0.15–0.29) | 0.30 (0.26–0.33) | −0.41 (−0.47 to −0.36) |
| 50–54 years | 44.03 (36.09–52.65) | 0.20 (0.11–0.28) | 0.67 (0.61–0.75) | −0.60 (−0.67 to −0.53) |
| 55–59 years | 74.97 (62.35–88.61) | 0.23 (0.17–0.28) | 1.29 (1.16–1.42) | −0.60 (−0.65 to −0.54) |
| 60–64 years | 135.60 (116.99–156.61) | 0.22 (0.18–0.27) | 3.00 (2.75–3.29) | −0.44 (−0.48 to −0.4) |
| 65–69 years | 286.60 (252.55–320.54) | 0.17 (0.12–0.23) | 8.17 (7.5–8.91) | −0.30 (−0.39 to −0.22) |
| 70–74 years | 620.55 (557.94–685.24) | 0.16 (0.1–0.22) | 24.15 (22.02–26.39) | −0.12 (−0.2 to −0.04) |
| 75–79 years | 1151.86 (1057.88–1253.43) | 0.23 (0.19–0.28) | 59.34 (54.33–64.85) | 0.05 (−0.01 to 0.1) |
| 80–84 years | 1664.64 (1482.48–1807.07) | 0.41 (0.36–0.46) | 112.07 (98.81–121.25) | 0.26 (0.2 to 0.32) |
| 85–89 years | 1958.79 (1695.2–2163.9) | 0.59 (0.53–0.66) | 168.38 (143.59–184.59) | 0.47 (0.39 to 0.55) |
| 90–94 years | 1902.67 (1590.46–2099.56) | 0.69 (0.64–0.73) | 189.17 (154.38–209.9) | 0.56 (0.5 to 0.61) |
| 95+ years | 1541.07 (1218.87–1749.86) | 0.63 (0.56–0.7) | 161.34 (120.38–183.81) | 0.54 (0.46 to 0.61) |
ASR, age-standardised rate; DALYs, disability-adjusted life years; EAPC, estimated annual percentage change; UI, uncertainty interval.