Clinical and treatment-related characteristics of HIV-infected adolescents receiving antiretroviral therapy in public hospitals, South Ethiopia, 2024
Variables | Categories | Frequency | Percentage |
Mode of entry | VCT | 77 | 18.8 |
Medical referral/linkage | 253 | 61.9 | |
Other* | 79 | 19.3 | |
Body mass index for age | <–2 SD | 185 | 45.2 |
≥− 2 SD | 224 | 54.8 | |
Haemoglobin level | <100 g/L | 28 | 6.9 |
≥100 g/L | 381 | 93.1 | |
WHO clinical staging | I | 227 | 55.5 |
II | 56 | 13.7 | |
III | 107 | 26.1 | |
IV | 19 | 4.7 | |
History of tuberculosis | Yes | 65 | 15.9 |
No | 344 | 84.1 | |
Treated for tuberculosis (n=65) | Yes | 61 | 93.9 |
No | 4 | 6.1 | |
Treatment regimen for tuberculosis | 2SRHZ/4RH | 5 | 7.7 |
2HRZE/4RH | 55 | 84.6 | |
Unknown | 5 | 7.7 | |
History of opportunistic infections other than tuberculosis | Yes | 74 | 18.1 |
No | 335 | 81.9 | |
Functional status | Working | 298 | 72.9 |
Ambulatory | 90 | 22.0 | |
Bedridden | 21 | 5.1 | |
Disclosure of HIV status to the adolescent | Yes | 265 | 64.8 |
No | 144 | 35.2 | |
Co-trimoxazole Prophylactic Therapy | Yes | 227 | 55.5 |
No | 182 | 44.5 | |
INH | Yes | 268 | 65.5 |
No | 141 | 34.5 | |
Type of initial regimen | TDF+3TC+EFV | 60 | 14.7 |
AZT+3TC+NVP | 157 | 34.4 | |
TDF+3TC+DTG | 69 | 16.9 | |
ABC+3TC+DTG | 34 | 8.3 | |
AZT+3TC+EFV | 23 | 5.6 | |
Other† | 66 | 16.1 | |
Month on antiretroviral therapy | <1 year | 55 | 13.5 |
1–4 years | 142 | 34.7 | |
≥5 years | 212 | 51.8 | |
Adherence | Good | 331 | 80.9 |
Fair | 30 | 7.3 | |
Poor | 48 | 11.7 | |
Regimen change | Yes | 265 | 64.8 |
No | 144 | 35.2 | |
Viral load (n=205) in copies/mL | Below 1000 | 180 | 87.8 |
1000 and above | 25 | 12.2 | |
CD4 count (n=281) in cells/mm3 | ≤200 | 50 | 17.8 |
200–350 | 47 | 16.7 | |
≥350 | 184 | 65.5 |
*Other: dried blood spots, index case testing and self-referral.
†Other: ABC+3TC+EFV, ABC+3TC+LPV/r, TDF+3TC+ATV/r.
ABC, abacavir ; ATV, atazanavir; AZT, zidovudine; DTG, dolutegravir; E, ethambutol; EFV, efavirenz; H, isoniazid; INH, isoniazid; LPV/r, lopinavir/ritonavir; NVP, nevirapine; R, rifampicin; S, streptomycin; 3TC, lamivudine; TDF, tenofovir; VCT, Voluntary Counseling and Testing; Z, pyrazinamide.