Table 1

Number and geographic location (continent) of active pharmaceutical ingredient (API) manufacturing sites and related medicinal products

Pharmaceutical substanceAPI manufacturing sites per continent (n)Related authorised medicinal products per continent (n)
TotalEuropeOther continentsTotalEuropeEurope and other continents*Other continents
Overall9038 (42%)52 (58%)407146 (36%)139 (34%)122 (30%)
Amoxicillin63 (50%)3 (50%)3224 (75%)0 (0%)8 (25%)
Colecalciferol53 (60%)2 (40%)8247 (57%)18 (22%)17 (21%)
Desloratadine153 (20%)12 (80%)340 (0%)15 (44%)19 (56%)
Diclofenac83 (38%)5 (62%)297 (24%)3 (10%)19 (66%)
Levonorgestrel/ethinylestradiol44 (100%)0 (0%)2121 (100%)0 (0%)0 (0%)
44 (100%)
Metoprolol136 (46%)7 (54%)3413 (38%)16 (47%)5 (15%)
Omeprazole126 (50%)6 (50%)8514 (16%)56 (66%)15 (18%)
Pantoprazole174 (24%)13 (76%)330 (0%)16 (48%)17 (52%)
Salbutamol65 (83%)1 (17%)2120 (95%)0 (0%)1 (5%)
Simvastatin112 (18%)9 (82%)360 (0%)15 (42%)21 (58%)
  • *The regulatory dossier for an authorised medicinal product may list several API manufacturers on different continents.