Table 3

Multivariable analyses of association between cardiovascular risk factors and the cognitive assessment results, older people living with HIV, Georgia, 2023 (n=122)

AssessmentFramingham risk scoreTotal cholesterol (units)HDL (units)Diabetes (yes/no)
β (95% CI)pβ (95% CI)pβ (95% CI)pβ (95% CI)p
MoCA0.001 (−0.08, 0.08)0.980.001 (−0.02, 0.03)0.7−0.02 (−0.09, 0.04)0.472.97 (−0.42, 6.36)0.09
TMT A0.35 (−0.12, 0.81)0.140.12 (−0.01, 0.24)0.07−0.08 (−0.44, 0.28)0.67−6.22 (−25.5, 13.1)0.53
TMT B1.65 (0.11, 3.19)0.04−0.2 (−0.6, 0.2)0.330.61 (−0.51, 1.73)0.284.92 (−53.22, 63.05)0.87
Semantic fluency−0.02 (−0.23, 0.19)0.80.03 (−0.03, 0.08)0.32−0.14 (−0.29, 0.02)0.088.51 (0.46, 16.57)0.04
Letter fluency−0.01 (−0.20, 0.17)0.9−0.05 (−0.10, 0.01)0.040.07 (−0.06, 0.21)0.2911.41 (4.31, 18.50)0.002
Stroop Test 1−0.19 (−0.61, 0.23)0.4−0.05 (−0.16, 0.07)0.42−0.12 (−0.44, 0.20)0.45−6.98 (−23.84, 9.88)0.41
Stroop Test 2−0.20 (−0.53, 0.13)0.23−0.004 (−0.09, 0.08)0.92−0.20 (−0.44, 0.04)0.114.07 (−8.63, 16.78)0.53
Stroop Test 3−0.04 (−0.31, 0.22)0.70.02 (−0.05, 0.09)0.57−0.04 (−0.23, 0.16)0.7211.07 (−9.44, 11.57)0.84
GPT1.02 (0.43, 1.60)0.0010.01 (−0.15, 0.16)0.93−0.30 (−0.73, 0.13)0.178.69 (−14.10, 31.47)0.45
  • Note: Multiple linear regression models were adjusted for BMI, years of education, drug dependency, having enough income for basic needs, history of HCV infection, history of tuberculosis, history of stroke, history of COVID-19 and history of ever interrupting ART

  • GPT, Grooved Pegboard Test; HDL, high-density lipoprotein; HIV, human immunodeficiency virus; TMT, trail-making test.