Table 1
Costs, quality-adjusted life years (QALYs) and cost-effectiveness for age and gender subgroups
| TSA mean | HA mean | Difference (HA – TSA) | ICER | |||||
| Cost (£) (95% CI) | QALYs (95% CI) | Cost (£) (95% CI) | QALYs (95% CI) | Costs (£) (95% CI) | QALYs (95% CI) | Cost per QALY (£) | (Probability of TSA cost-effective) | |
| Female≤60 | 9223 (9160, 9287) | 13.63 (13.5, 13.8) | 9882 (9817, 9946) | 11.64 (11.5, 11.8) | 658 (581,735) | −1.99 (−2.2, 1.8) | TSA dominant −331 | 69% |
| Male≤60 | 8610 (8553, 8666) | 13.01 (12.9, 13.2) | 9073 (9012, 9133) | 11.00 (10.8, 11.2) | 463 (387,538) | −2.01 (−2.3, 1.8) | TSA dominant −230 | 71% |
| Female 61–75 | 7548 (7493, 7602) | 9.30 (9.2, 9.4) | 7367 (7316, 7418) | 7.85 (7.7, 8.0) | −181 (−253, 109) | −1.44 (−1.6, 1.26) | 126 | 69% |
| Male 61–75 | 7291 (7238, 7344) | 8.51 (8.4, 8.6) | 6895 (6846, 6945) | 7.25 (7.1, 7.4) | −395 (−466, 325) | −1.26 (−1.4, 1.1) | 314 | 68% |
| Female>75 | 6861 (6808, 6914) | 5.26 (5.2, 5.3) | 5895 (5848, 5943) | 4.32 (4.2, 4.4) | −966 (−1038, −893) | −0.94 (−1.1, 0.8) | 1024 | 70% |
| Male>75 | 6807 (6754, 6859) | 4.60 (4.5, 4.7) | 5902 (5854, 5950) | 3.87 (3.8, 3.9) | −905 (−976, 833) | −0.73 (−0.8, 0.6) | 1236 | 68% |
95% CI is estimated using the SE of the mean, SEM=SD/
, where SD is the sample SD of the 1000 random draws in the PSA.HA, hemiarthroplasty; ICER, incremental cost-effectiveness ratio; PSA, probabilistic sensitivity analysis; TSA, total shoulder arthroplasty.