Table 1

Demographic and clinical characteristics of patients with incident gout included in analysis 1

Not exposedExposed to 100 mgExposed to >100 mg
Men
n=9405
Women
n=4848
Men
n=1941
Women
n=951
Men
n=1287
Women
n=430
Age, mean (SD), years62.3 (14.5)68.5 (14.7)67.7 (13.8)76.5 (11.6)63.6 (13.5)74.5 (11.3)
Follow-up, years, median (Q1, Q3)4.1 (1.9, 6.7)4.1 (1.9, 6.7)4.4 (1.9, 7.0)3.7 (1.6, 6.2)5.0 (2.5, 7.6)4.1 (1.9, 6.3)
Education level, years
<92901 (30.9)1899 (39.2)742 (38.2)509 (53.5)446 (34.7)207 (48.1)
9–124275 (45.5)1945 (40.1)803 (41.4)313 (32.9)537 (41.7)159 (37.0)
>122090 (22.2)932 (19.2)361 (18.6)109 (11.5)271 (21.1)56 (13.0)
Comorbidity index*, N(%)
02254 (24.0)845 (17.4)217 (11.2)†20 (2.1)†1732 (13.4)†5 (1.2)†
1–23517 (37.4)1877 (38.7)600 (30.9)†228 (24.0)†394 (30.6)†104 (24.2)†
3–42666 (28.4)1527 (31.5)709 (36.5)†433 (45.5)†446 (34.7)†194 (45.1)†
≥5968 (10.3)599 (12.4)415 (21.4)†270 (28.4)†275 (21.4)†127 (29.5)†
Medication‡, N(%)
Anticoagulants/platelet aggregation inhibitors2956 (31.4)1630 (33.6)917 (47.2)†549 (57.7)†544 (42.3)†240 (55.8)†
CV drugs§5032 (53.5)3066 (63.2)1515 (78.1)†891 (93.7)†971 (75.4)†404 (94.0)†
Cortisone854 (9.1)600 (12.4)312 (16.1)†217 (22.8)†203 (15.8)†88 (20.5)†
  • *Based on the number of ever diagnosed comorbidities during the follow-up. Comorbidities included: hypertension, diabetes, hyperlipidaemia, obesity, renal disease, heart failure, cardiomyopathy, psoriasis, chronic obstructive pulmonary disease, alcoholism, cerebrovascular disease, atherosclerotic disease and cancer.

  • †p<0.05 compared with those not exposed.

  • ‡Defined as dispensed prescription within 6 months before the end of follow-up.

  • §Drugs included: vasodilator drugs, anti-hypertensive drugs, diuretics, beta blockers, calcium antagonists and renin-angiotensin-aldosterone inhibitors.

  • CV, cardiovascular.