The sensitivity analysis presents the risk of 30-day and 90-day mortality following IHT, categorised by pandemic waves
Risk of death for IHT by COVID-19 wave | |||||||
Waves | Exposure | Mortality | 30-day mortality | 90-day mortality | |||
No (%) | 30-day No (%) | 90-day No (%) | Unadjusted HR with 95% CI | Adjusted HR with 95% CI | Unadjusted HR with 95% CI | Adjusted HR with 95% CI | |
Wave 1 | |||||||
Non-IHT | 218 (82) | 61 (28) | 64 (29) | 1.0 (referent) | 1.0 (referent) | 1.0 (referent) | 1.0 (referent) |
IHT | 47 (18) | 4 (9) | 7 (15) | 0.26 (0.10 to 0.73)* | 0.24 (0.08 to 0.66)* | 0.44 (0.20 to 0.96)* | 0.38 (0.17 to 0.85)* |
Waves 2–3 | |||||||
Non-IHT | 314 (78) | 75 (24) | 93 (30) | 1.0 (referent) | 1.0 (referent) | 1.0 (referent) | 1.0 (referent) |
IHT | 86 (22) | 21 (24) | 27 (31) | 0.95 (0.58 to 1.54) | 0.68 (0.38 to 1.18) | 1.01 (0.65 to 1.54) | 0.63 (0.38 to 1.04) |
The analyses are presented as HR with 95% CI, using non-IHT patients as the reference group.
The models were adjusted for age, sex, body mass index categories (<30 or >30), Simplified Acute Physiology Score, Charlson Comorbidity Index 0, 1, >2) mechanical ventilation (yes/no), treatment limitations (yes/no) and SARS-CoV-2 wave (wave 1/waves 2–3).
*Statistically significant differences between groups, p<0.05.
IHT, interhospital transfer.