Table 4

The sensitivity analysis presents the risk of 30-day and 90-day mortality following IHT, categorised by pandemic waves

Risk of death for IHT by COVID-19 wave
WavesExposureMortality30-day mortality90-day mortality
No (%)30-day
No (%)
90-day
No (%)
Unadjusted
HR with 95% CI
Adjusted
HR with 95% CI
Unadjusted
HR with 95% CI
Adjusted
HR with 95% CI
Wave 1
 Non-IHT218 (82)61 (28)64 (29)1.0 (referent)1.0 (referent)1.0 (referent)1.0 (referent)
 IHT47 (18)4 (9)7 (15)0.26 (0.10 to 0.73)*0.24 (0.08 to 0.66)*0.44 (0.20 to 0.96)*0.38 (0.17 to 0.85)*
Waves 2–3
 Non-IHT314 (78)75 (24)93 (30)1.0 (referent)1.0 (referent)1.0 (referent)1.0 (referent)
 IHT86 (22)21 (24)27 (31)0.95 (0.58 to 1.54)0.68 (0.38 to 1.18)1.01 (0.65 to 1.54)0.63 (0.38 to 1.04)
  • The analyses are presented as HR with 95% CI, using non-IHT patients as the reference group.

  • The models were adjusted for age, sex, body mass index categories (<30 or >30), Simplified Acute Physiology Score, Charlson Comorbidity Index 0, 1, >2) mechanical ventilation (yes/no), treatment limitations (yes/no) and SARS-CoV-2 wave (wave 1/waves 2–3).

  • *Statistically significant differences between groups, p<0.05.

  • IHT, interhospital transfer.