Study drug schedule
| Study day | Morning dose (n tablets) | Evening dose (n tablets) | Total daily dose (mg naltrexone/mg bupropion) |
| 1 | 1 | 0 | 8/90 |
| 2 | 1 | 1 | 16/180 |
| 3 | 2 | 1 | 24/270 |
| 4 | 2 | 2 | 32/360 |
| 5–84 | 3 | 2 | 40/450 |
| 85 | 2 | 2 | 32/360 |
| 86 | 2 | 1 | 24/270 |
| 87 | 1 | 1 | 16/180 |
| 88* | 1 | 0 | 8/90 |
| 89 | 0 | 0 | 0 |
*Day 88 is the final study drug dose.