Table 4

Univariable and multivariable predictors of new pacemaker implantation following TAVI

	Univariable						Multivariable
	N	Events	OR	95% CI	P value	OR	95% CI	P value
General predictors
Age (year)	548	173	1.02	0.99, 1.05	0.15
Male sex	548	173	1.20	0.84, 1.72	0.32
BMI (kg/m²)	548	173	1.02	0.98, 1.06	0.41
Hypertension	548	173	1.16	0.69, 1.94	0.57
Chronic kidney disease	548	173	0.96	0.64, 1.44	0.85
Diabetes mellitus	548	173	1.17	0.74, 1.85	0.51
Cardiovascular disease	548	173	1.16	0.77, 1.73	0.48
Atrial fibrillation	548	173	1.84	1.25, 2.70	0.002	1.89	1.24, 2.88	0.003*
Heart rate (bpm)	548	173	0.99	0.97, 1.00	0.098	0.99	0.97, 1.00	0.056
ECG predictors
Abnormal ECG	548	173	1.91	1.31, 2.80	<0.001	1.73	1.14, 2.63	0.010
Sokolow-Lyon product (mv)	548	173	0.92	0.77, 1.09	0.32
ECG LVH by Sokolow-Lyon	548	173	0.92	0.62, 1.38	0.69
R amplitude (mm)	548	173	0.99	0.95, 1.02	0.43
ECG LVH by R amplitude	548	173	0.89	0.60, 1.32	0.56
ECG LVH by R or Sokolow	548	173	0.89	0.60, 1.32	0.39
QRS complex duration (ms)	548	173	1.01	1.00, 1.02	0.063
Right bundle branch block	548	173	1.93	1.05, 3.56	0.034	2.23	1.09, 4.59	0.028
Left bundle branch block	548	173	1.50	0.83, 2.73	0.18
Bifascicular block	548	173	0.54	0.11, 2.55	0.43
Echocardiographic predictors
BSH	548	173	0.79	0.55, 1.15	0.21
ASH	548	173	1.18	0.76, 1.83	0.45
Aortic root (cm)	547	173	2.07	1.30, 3.29	0.002	1.65	0.99, 2.75	0.052
Annulus (cm)	547	173	1.50	0.54, 4.16	0.44
Stroke volume index (ml/m²)	539	172	1.00	0.99, 1.02	0.61
Mean pressure gradient (mmHg)	548	173	1.00	0.98, 1.01	0.41
Aortic valve area (cm²)	541	172	1.29	0.64, 2.62	0.48
EF Simpson (%)	548	173	1.00	0.98, 1.02	0.88
SEV	548	173	0.70	0.48, 1.04	0.075
1. Generation			1.82	1.21 to 2.73	0.004
2. Generation			0.62	0.41 to 0.94	0.024
3. Generation			0.40	0.19 to 0.84	0.016
Intra-annular			0.73	0.36 to 1.48	0.381
Mechanically expandable valve	548	173	4.22	2.68, 6.66	<0.001	3.48	2.16, 5.59	<0.001
BEV	548	173	0.06	0.01, 0.24	<0.001	0.07	0.02, 0.29	<0.001
Valve size (mm)	548	173	1.03	0.96, 1.09	0.41

*Abnormal ECG was replaced by atrial fibrillation in the same model.
ASH, asymmetrical septal hypertrophy; BEV, balloon-expandable valve; BMI, body mass index; BSH, Basal septal hypertrophy; EF, ejection fraction; SEV, self-expanding valve; TAVI, transcatheter aortic valve implantation.