Independent factors associated with high hepatic transaminases as determined by logistic regression*
Factor | Adjusted OR for high transaminases | 95% CI | P value |
HbE β-thalassaemia type | 13.6 | 2.00 to 92.7 | 0.008 |
High ferritin>1000 ng/dL | 6.25 | 1.02 to 38.2 | 0.047 |
Deferasirox treatment | 4.20 | 0.57 to 30.6 | 0.15 |
Hepatomegaly | 1.97 | 0.53 to 7.35 | 0.31 |
Deferoxamine treatment | 0.63 | 0.16 to 2.46 | 0.51 |
*High hepatic transaminases are defined as ALT>40 IU/L and AST>40 IU/L.
ALT, alanine transaminases; AST, aspartate transaminases; HbE, haemoglobin E.