Table 4

Independent factors associated with high hepatic transaminases as determined by logistic regression*

FactorAdjusted OR for high transaminases95% CIP value
HbE β-thalassaemia type13.62.00 to 92.70.008
High ferritin>1000 ng/dL6.251.02 to 38.20.047
Deferasirox treatment4.200.57 to 30.60.15
Hepatomegaly1.970.53 to 7.350.31
Deferoxamine treatment0.630.16 to 2.460.51
  • *High hepatic transaminases are defined as ALT>40 IU/L and AST>40 IU/L.

  • ALT, alanine transaminases; AST, aspartate transaminases; HbE, haemoglobin E.