Table 5

Factors associated with low eGFR as determined by χ2 test

FactorProportion in low eGFR groupProportion in normal eGFR groupχ2 valueP value
Type of thalassaemia
 β-thalassaemia major (n=43)10 (23.3%)33 (76.7%)3.620.05
 HbE β-thalassaemia (n=22)1 (4.5%)21 (95.5%)
Transfusion status
 Transfusion-dependent thalassaemia (n=54)10 (18.5%)44 (81.5%)1.570.20
 Non-transfusion-dependent thalassaemia (n=17)1 (5.9%)16 (94.1%)
Serum ferritin
 High (>1000 ng/mL) (n=42)6 (14.3%)36 (85.7%)0.110.73
 Normal (<1000 ng/mL) (n=29)5 (17.2%)24 (82.8%)
Deferasirox treatment
 On deferasirox (n=54)10 (18.5%)44 (81.5%)1.570.20
 Not on deferasirox (n=17)1 (5.9%)16 (94.1%)
Deferoxamine treatment
 On desferioxamine (n=30)5 (16.7%)25 (83.3%)0.550.81
 Not on desferioxamine (n=41)6 (14.6%)35 (85.4%)
  • eGFR, estimated glomerular filtration rate; HbE, haemoglobin E.