Factors associated with low eGFR as determined by χ2 test
Factor | Proportion in low eGFR group | Proportion in normal eGFR group | χ2 value | P value |
Type of thalassaemia | ||||
β-thalassaemia major (n=43) | 10 (23.3%) | 33 (76.7%) | 3.62 | 0.05 |
HbE β-thalassaemia (n=22) | 1 (4.5%) | 21 (95.5%) | ||
Transfusion status | ||||
Transfusion-dependent thalassaemia (n=54) | 10 (18.5%) | 44 (81.5%) | 1.57 | 0.20 |
Non-transfusion-dependent thalassaemia (n=17) | 1 (5.9%) | 16 (94.1%) | ||
Serum ferritin | ||||
High (>1000 ng/mL) (n=42) | 6 (14.3%) | 36 (85.7%) | 0.11 | 0.73 |
Normal (<1000 ng/mL) (n=29) | 5 (17.2%) | 24 (82.8%) | ||
Deferasirox treatment | ||||
On deferasirox (n=54) | 10 (18.5%) | 44 (81.5%) | 1.57 | 0.20 |
Not on deferasirox (n=17) | 1 (5.9%) | 16 (94.1%) | ||
Deferoxamine treatment | ||||
On desferioxamine (n=30) | 5 (16.7%) | 25 (83.3%) | 0.55 | 0.81 |
Not on desferioxamine (n=41) | 6 (14.6%) | 35 (85.4%) |
eGFR, estimated glomerular filtration rate; HbE, haemoglobin E.