Patient characteristics according to the tertiles of NT-pro BNP levels
| Total (n=829) | NT-pro BNP tertiles, pg/mL | |||
| T1 (≤150.3) (n=276) | T2 (150.3–667.6) (n=277) | T3 (>667.6) (n=276) | ||
| Baseline characteristics | ||||
| Age, years | 55.1±13.1 | 50.1±11.5 | 58.7±13.0 | 56.5±13.2 |
| Male | 587 (70.8) | 224 (81.2) | 176 (63.5) | 187 (67.8) |
| Heart rate | 79.4±18.1 | 75.8±14.6 | 80.3±18.2 | 82.2±20.6 |
| Admission SBP (mm Hg) | 144.5±31.9 | 149.5±30.6 | 143.8±31.9 | 140.1±32.5 |
| Admission DBP (mm Hg) | 77.3±19.8 | 80.3±19.9 | 77.0±18.1 | 74.5±21.1 |
| Diabetes mellitus | 40 (4.8) | 16 (5.8) | 17 (6.1) | 7 (2.5) |
| Hypertension | 690 (83.2) | 232 (84.1) | 236 (85.2) | 222 (80.4) |
| Hyperlipidaemia | 180 (21.7) | 64 (23.2) | 58 (20.9) | 58 (21.0) |
| Smoking | 264 (31.8) | 111 (40.2) | 85 (30.7) | 68 (24.6) |
| Coronary artery disease | 123 (14.8) | 26 (9.4) | 43 (15.5) | 54 (19.6) |
| Previous stroke | 63 (7.6) | 18 (6.5) | 27 (9.7) | 18 (6.5) |
| Previous aortic disease | 22 (2.7) | 3 (1.1) | 13 (4.7) | 6 (2.2) |
| Previous replacement of aorta valve | 12 (1.4) | 0 (0) | 3 (1.1) | 9 (3.3) |
| Syncope | 61 (7.4) | 9 (3.3) | 23 (8.3) | 29 (10.5) |
| Coma | 14 (1.7) | 6 (2.2) | 6 (2.2) | 2 (0.7) |
| Shock | 35 (4.2) | 6 (2.2) | 9 (3.2) | 20 (7.2) |
| Time from onset to admission, hours | 12.0 (7.0–24.0) | 7.0 (5.0–13.0) | 12.0 (7.0–24.0) | 22.0 (10.0–48.0) |
| In-hospital assessment | ||||
| Left ventricular diameter, mm | 49.9±7.4 | 49.3±6.7 | 48.7±6.8 | 51.7±8.3 |
| Left ventricular ejection fraction, % | 58.8±7.7 | 60.6±4.9 | 59.1±6.7 | 56.5±10.0 |
| Aortic valve regurgitation | 210 (25.4) | 47 (17.0) | 61 (22.2) | 102 (37.1) |
| Pericardial effusion | 61 (7.4) | 12 (4.3) | 20 (7.3) | 29 (10.5) |
| Artery affected | ||||
| Coronary artery | 213 (27.0) | 61 (22.8) | 70 (26.7) | 82 (31.7) |
| Brachiocephalic trunk | 522 (66.2) | 165 (61.6) | 177 (67.6) | 180 (69.5) |
| Coeliac axis | 227 (28.8) | 80 (29.9) | 64 (24.4) | 83 (32.0) |
| Superior mesenteric artery | 198 (25.1) | 69 (25.7) | 62 (23.7) | 67 (25.9) |
| Renal artery | 211 (26.7) | 66 (24.6) | 71 (27.1) | 74 (28.6) |
| Iliac artery | 298 (37.8) | 100 (37.3) | 92 (35.1) | 100 (37.3) |
| Baseline biomarkers | ||||
| NT-proBNP, pg/mL | 308.0 (104.8–974.5) | 74.0 (40.7–105.4) | 308.0 (219.0–444.9) | 1490.5 (974.3–3108.5) |
| ln NT-proBNP | 5.8±1.6 | 4.1±0.7 | 5.7±0.4 | 7.6±0.9 |
| Haemoglobin, g/dL | 134.8±19.2 | 140.3±18.8 | 133.8±16.8 | 130.3±20.5 |
| D-dimerse, mg/L | 10.9 (3.8–20.0) | 11.3 (3.4–20.0) | 12.5 (4.1–20.0) | 9.9 (3.7–20.0) |
| Creatinine, μmol/L | 110.9±58.2 | 94.8±32.1 | 100.4±38.6 | 137.5±81.1 |
| C reactive protein, mg/L | 11.4 (4.6–53.2) | 6.4 (3.3–14.8) | 12.8 (5.1–53.3) | 26.4 (9.0–80.3) |
| Troponin I (TnI), ng/mL | 0 (0–0.04) | 0 (0–0) | 0 (0–0.05) | 0.03 (0–0.21) |
| Treatment | ||||
| Conservative treatment | 305 (36.8) | 62 (22.5) | 106 (38.3) | 137 (49.6) |
| Surgery treatment | 524 (63.2) | 214 (77.5) | 171 (61.7) | 139 (50.4) |
Values are median (IQR) or n (%).
DBP, diastolic blood pressure; NT-proBNP, N-terminal pro-brain natriuretic peptide; SBP, stress blood pressure.