Table 1

Inclusion and exclusion criteria

Inclusion criteriaExclusion criteria
18–59 years old adultsIndividuals on immunosuppressant (ie, steroids)
Moderate stress (scoring Perceived Stress Scale 10 within 14–26)Usage of immune-modifying medications or dietary supplements affecting the immune system
(at least 2 weeks of washing period for inclusion)
Scored Patient Health Questionnaire 9 less than or equal to 9Any autoimmune or health concerns
Individuals with symptoms of common colds for the past 6 months assess using Jackson Cold ScaleUncontrolled comorbidities including diabetes, hypertension, cardiovascular disease, chronic kidney disease, chronic liver disease, active malignancy, endocrine disorder and cancer
Willing to comply with protocol requirementsUncontrolled chronic respiratory illness including allergic rhinitis or asthma, presence of nasal ulcers/polyps
Body temperature >38°C at study commencement (fever)
Pregnant or lactating female
On specific dietary requirements (diabetic diet/low salt diet/etc)
On prebiotics or probiotics supplementation (at least 2 weeks of washing period for inclusion)
On antibiotics washing period within 2 weeks for inclusion
Individuals with disabilities (long-term physical, mental, intellectual and sensory impairment)
Individuals without symptoms of common colds for the past 6 months
Allergy to yeast, oat, wheat, barley
Influenza vaccination for the past 1 year
Pneumococcal Polysaccharide Vaccine-23/PSV23 (Pneumovax-23) in the last 5 years and those who had received Pneumococcal Conjugate Vaccine/PCV 13 (Prevenar 13)
Participate in another research study