Population characteristics of the included sources
| Study population | Number | Mean age range (years) | Percentage female (range) | Relevant citations |
| Total interventional study participants | 71362 | 54.45–88 | 32–75 | 26 30–34 47–51 54 78 79 83 84 94 95 100 101 103 105–108 110 112 114 |
| Total non-interventional study participants | 213 877 | 33.4–84.6 | 0–77 | 20–24 35–39 52 53 55–63 77 80 81 85–88 96 97 99 111 115–120 |
| Total systematic review participants | 21820 across 68 reviewed original studies | 65.95–82.5 | 39–61 | 6–8 64–66 121 |