Baseline and changes of CAC according to serum albumin tertiles
| Total (n=12 344) | Tertiles of serum albumin | P value | |||
| I (lowest) (n=3111) 3.5–4.2 g/dL | II (n=5241) 4.3–4.5 g/dL | III (highest) (n=3992) 4.6–5.5 g/dL | |||
| Baseline | |||||
| Categorical CACS | 0.022 | ||||
| 0 | 6937 (56.2) | 1738 (55.9) | 2930 (55.9) | 2269 (56.8) | |
| 1–10 | 1723 (14.0) | 456 (14.7) | 772 (14.7) | 495 (12.4) | |
| 11–100 | 2381 (19.3) | 575 (18.5) | 996 (19.0) | 810 (20.3) | |
| >100 | 1303 (10.6) | 342 (11.0) | 543 (10.4) | 418 (10.5) | |
| Follow-up | |||||
| Categorical CACS | <0.001 | ||||
| 0 | 5771 (46.8) | 1396 (44.9) | 2391 (45.6) | 1984 (49.7) | |
| 1–10 | 1054 (8.5) | 243 (7.8) | 482 (9.2) | 329 (8.2) | |
| 11–100 | 2836 (23.0) | 711 (22.9) | 1212 (23.1) | 913 (22.9) | |
| >100 | 2683 (21.7) | 761 (24.5) | 1156 (22.1) | 766 (19.2) | |
| Δ √transformed CACS | 0 (0–3.46) | 0.39 (0–4.62) | 0 (0–3.61) | 0 (0–2.51) | <0.001 |
| Annualised Δ √transformed CACS | 0 (0–1.10) | 0.16 (0–1.24) | 0 (0–1.09) | 0 (0–1.01) | <0.001 |
| CAC progression, n (%) | |||||
| Overall | 3780 (30.6) | 1138 (36.6) | 1643 (31.3) | 999 (25.0) | <0.001 |
| Categorical CACS at baseline | |||||
| 0 | 902 (13.0) | 271 (15.6) | 401 (13.7) | 230 (10.1) | <0.001 |
| 1–10 | 992 (57.6) | 299 (65.6) | 473 (61.3) | 220 (44.4) | <0.001 |
| 11–100 | 1201 (50.4) | 361 (62.8) | 499 (50.1) | 341 (42.1) | <0.001 |
| >100 | 685 (52.6) | 207 (60.5) | 270 (49.7) | 208 (49.8) | 0.003 |
Values are given as the median (IQR), or number (%).
CAC, coronary artery calcification; CACS, coronary artery calcium score.