Comparisons of clinical and laboratory characteristics among patients with different stone composition groups
| Variable | Overall, n=704 | CaOx, n=560 | Infection stones, n=80 | UA, n=32 | Others, n=32 | P value* |
| BMI (kg/m*) | 24.7 (3.3) | 24.7 (3.3) | 24.2 (3.1) | 25.4 (3.7) | 24.2 (4.3) | 0.309 |
| History of urolithiasis | 210 (32.7)† | 161 (31.8)‡ | 31 (41.3)§ | 12 (40.0)¶ | 6 (20.0)¶ | 0.129 |
| Family history of urolithiasis | 42 (6.6)* | 33 (6.5)** | 5 (6.7)§ | 2 (6.7)¶ | 2 (6.7)¶ | >0.999 |
| Comorbidities | ||||||
| Prostatic hyperplasia | 62 (8.8) | 43 (7.7) | 5 (6.3) | 13 (40.6) | 1 (3.1) | <0.001 |
| Dyslipidaemia | 77 (10.9) | 57 (10.2) | 9 (11.2) | 6 (18.8) | 5 (15.6) | 0.307 |
| Diabetes | 60 (8.5) | 50 (8.9) | 2 (2.5) | 8 (25.0) | 0 (0) | 0.001 |
| Hypertension | 141 (20.0) | 118 (21.1) | 9 (11.2) | 12 (37.5) | 2 (6.3) | 0.003 |
| Kidney disease | 32 (4.6) | 19 (3.4) | 4 (5.0) | 9 (28.1) | 0 (0) | <0.001 |
| CVD | 43 (6.1) | 36 (6.4) | 2 (2.5) | 5 (15.6) | 0 (0) | 0.038 |
| Cancer | 20 (2.8) | 18 (3.2) | 1 (1.3) | 1 (3.1) | 0 (0) | 0.701 |
| Laboratory indexes | ||||||
| WBC 109 /L | 7.06 (5.77, 9.22) | 6.99 (5.72, 9.22) | 7.32 (6.14, 9.21) | 8.24 (6.63, 10.36) | 6.50 (5.36, 7.90) | 0.046 |
| RBC 1012 /L | 4.77 (4.42, 5.08) | 4.78 (4.43, 5.09) | 4.76 (4.48, 5.05) | 4.51 (4.12, 4.80) | 4.84 (4.54, 5.10) | 0.026 |
| HGB g/L | 141.71 (16.05) | 142.43 (15.79) | 140.90 (16.63) | 132.44 (16.27) | 140.38 (16.69) | 0.005 |
| PLR | 137.25 (107.25, 182.26) | 132.94 (106.72, 175.79) | 154.05 (119.56, 198.18) | 158.00 (113.84, 228.39) | 152.38 (107.73, 188.35) | 0.032 |
| UA mg/dL | 6.59 (1.70) | 6.60 (1.73) | 6.35 (1.40) | 7.20 (1.81) | 6.27 (1.66) | 0.182 |
| BUN | 5.28 (4.30,6.30) | 5.30 (4.39,6.30) | 4.88 (4.23,5.70) | 6.85 (6.23,8.07) | 4.80 (3.94, 5.50) | <0.001 |
| Cr μmoI/L | 0.92 (0.76, 1.13) | 0.91 (0.77, 1.10) | 0.91 (0.73, 1.12) | 1.25 (0.87, 1.51) | 0.93 (0.72, 1.08) | 0.004 |
| ALB g/L | 43.90 (41.20, 46.70) | 43.70 (41.20, 46.58) | 44.80 (41.30, 46.90) | 41.60 (38.10, 44.50) | 45.60 (41.85, 47.20) | 0.007 |
| TC mg/dL | 4.61 (3.93, 5.22) | 4.62 (3.94, 5.26) | 4.61 (4.07, 5.24) | 4.01 (3.38, 4.70) | 4.71 (4.16, 5.20) | 0.038 |
| TG mg/dL | 1.38 (0.98,1.96) | 1.39 (1.01, 1.97) | 1.27 (0.93, 1.69) | 1.77 (1.29, 2.65) | 1.37 (0.72, 1.88) | 0.023 |
| GGT U/L | 28.12 (18.92, 42.00) | 29.31 (19.32, 43.42) | 23.58 (17.68, 39.38) | 27.24 (20.52, 40.69) | 19.53 (16.69, 29.06) | 0.017 |
| UPH | 6.0 (5.5, 6.5) | 6.0 (5.5, 6.5) | 6.5 (6.0, 7.0) | 5.5 (5.0, 6.0) | 6.0 (6.0, 7.0) | <0.001 |
| Nitrite (positive) | 12 (1.7) | 6 (1.1) | 2 (2.5) | 2 (6.3) | 2 (6.3) | 0.014 |
| U-LEU (positive) | 308 (43.9)†† | 238 (42.7)‡‡ | 31 (38.8) | 22 (68.8) | 17 (53.1) | 0.016 |
Note: n (%), Kruskal-Wallis rank sum test; Fisher’s exact test; Pearson’s χ2 test.
Others refer to the mixed stone, SA and brushite.
*N=642,
†N=642,
‡N=507,
§N=75,
¶N=30.
**N=505,
††N=702,
‡‡N=558,
ALB, albumin; BMI, body mass index; BUN, blood urea nitrogen; CaOx, calcium oxalate; Cr, creatinine; CVD, cardiovascular disease; GGT, gamma-glutamyltransferase; HGB, haemoglobin; PLR, platelet-to-lymphocyte count ratio; RBC, red blood cells; TC, total cholesterol; TG, triglyceride; UA, uric acid; U-LEU, urinary leucocytes; UPH, urine pondus hydrogenii; WBC, white blood cells.