Overview study procedures
| Procedures (time needed) | Baseline visit (V1) | First treatment visit (T1) | Additional treatment visits (T2 up to T14) | Post-treatment visit (V2) | Follow-up visit (V3) |
| Medical history* | X | ||||
| Physical health* | X | X | |||
| Current medication use* | X | X | X | X | X |
| Clinical Frailty Scale* | X | ||||
| Sensation questionnaire (5 min) | X | X | |||
| Blinding and subjective treatment experience (1 min) | X | X | |||
| Feasibility questionnaire (5 min) | X | ||||
| Delirium interview (10 min) | X | ||||
| ICDSC (10 min) | X | X | X | X | |
| DOSS (5 min)† | X | X | X | X | |
| TICS-M (10 min) | X | ||||
| EEG (40 min) | X‡ | X | X | ||
| tACS (30 min) | X | X | |||
| Estimated total duration | 25 or 60 min‡ | 95 min | 45 min | 65 min | 15 min |
*This information will be recorded as part of standard clinical care, and missing information will be requested via family and will therefore not require additional time.
†Only non-intensive care unit patients will be assessed using the DOSS.
‡Only the group randomised to personalised tACS will receive an EEG during the baseline visit.
DOSS, Delirium Observation Screening Scale; EEG, Electroencephalogram; ICDSC, Intensive Care Delirium Screening Checklist; tACS, transcranial altering current stimulation; TICS-M, Telephone Interview for Cognitive status, modified version.