Table 1

Overview study procedures

Procedures (time needed)Baseline visit (V1)First treatment visit (T1)Additional treatment visits (T2 up to T14)Post-treatment visit (V2)Follow-up visit (V3)
Medical history*X
Physical health*XX
Current medication use*XXXXX
Clinical Frailty Scale*X
Sensation questionnaire (5 min)XX
Blinding and subjective treatment experience (1 min)XX
Feasibility questionnaire (5 min)X
Delirium interview (10 min)X
ICDSC (10 min)XXXX
DOSS (5 min)†XXXX
TICS-M (10 min)X
EEG (40 min)X‡XX
tACS (30 min)XX
Estimated total duration25 or 60 min‡95 min45 min65 min15 min
  • *This information will be recorded as part of standard clinical care, and missing information will be requested via family and will therefore not require additional time.

  • †Only non-intensive care unit patients will be assessed using the DOSS.

  • ‡Only the group randomised to personalised tACS will receive an EEG during the baseline visit.

  • DOSS, Delirium Observation Screening Scale; EEG, Electroencephalogram; ICDSC, Intensive Care Delirium Screening Checklist; tACS, transcranial altering current stimulation; TICS-M, Telephone Interview for Cognitive status, modified version.