Comparison of clinical data between the survival and death groups
| Variable | All (n=4343) | Survival group (n=4017) | Death group (n=326) | P |
| Age, months | 22 (6–69) | 23 (6–70) | 16 (5–48) | 0.002 |
| Male, n (%) | 2540 (58.5) | 2333 (58.1) | 207 (63.5) | 0.056 |
| ICU type, n (%) | <0.001 | |||
| General ICU | 973 (22.4) | 825 (20.5) | 148 (45.4) | |
| Paediatric ICU | 1262 (29.1) | 1126 (28.0) | 136 (41.7) | |
| Surgical ICU | 2108 (48.5) | 2066 (51.4) | 42 (12.9) | |
| Cause for admission, n(%) | <0.001 | |||
| Respiratory system | 750 (17.3) | 650 (16.2) | 100 (30.7) | |
| Circulatory system | 235 (5.4) | 187 (4.7) | 48 (14.7) | |
| Digestive system | 920 (21.2) | 898 (22.4) | 22 (6.7) | |
| Nervous system | 1339 (30.8) | 1270 (31.6) | 69 (21.2) | |
| Urogenital system | 189 (4.4) | 186 (4.6) | 3 (0.9) | |
| Hematologic system | 333 (7.7) | 276 (6.9) | 57 (17.5) | |
| Other | 577 (13.3) | 550 (13.7) | 27 (8.3) | |
| Vital signs | ||||
| Body temperature, ℃ | 36.9 (36.4–37.4) | 36.9 (36.5–37.4) | 36.9 (36.0–37.6) | 0.464 |
| Heart rate, beats/min | 126 (108–144) | 126 (108–144) | 139 (113–158) | 0.001 |
| Respiratory rate, breaths/min | 28 (24–32) | 28 (24–32) | 35 (28–48) | <0.001 |
| Systolic pressure, mmHg | 106 (96–117) | 106 (96–118) | 92 (83–113) | <0.001 |
| Diastolic pressure, mmHg | 63 (54–72) | 63 (54–72) | 56 (45–67) | <0.001 |
| Laboratory data | ||||
| White blood cell, 109 /L | 9.63 (6.46–14.17) | 9.63 (6.46–13.98) | 10.14 (6.73–16.59) | 0.022 |
| Platelet, 109 /L | 297 (206–384) | 297 (213–386) | 253 (109–359) | <0.001 |
| Sodium, mmol/L | 137 (134–139) | 137 (134–139) | 137 (133–141) | 0.081 |
| Potassium, mmol/L | 3.8 (3.4–4.1) | 3.8 (3.4–4.1) | 3.9 (3.4–4.5) | <0.001 |
| Glucose, mmol/L | 6.7 (5.6–8.7) | 6.7 (5.7–8.6) | 6.7 (5.2–10.9) | 0.662 |
| Albumin, g/L | 36.8 (32.6–40.8) | 36.8 (32.9–40.8) | 35.5 (29.6–40.2) | <0.001 |
| APTT, s | 33.9 (28.8–43.2) | 33.9 (28.8–42.9) | 33.9 (30.1–46.5) | 0.079 |
| Ionised calcium, mmol/L | 1.21 (1.12–1.28) | 1.21 (1.13–1.28) | 1.12 (1.03–1.21) | <0.001 |
| PH | 7.375 (7.317–7.428) | 7.377 (7.321–7.430) | 7.336 (7.195–7.398) | <0.001 |
| Lactate, mmol/L | 1.7 (1.2–2.7) | 1.7 (1.2–2.5) | 3.2 (1.7–7.2) | <0.001 |
| Comorbidities, n (%) | ||||
| Anaemia | 2938 (67.6) | 2711 (67.5) | 227 (69.6) | 0.426 |
| Acute kidney injury | 459 (10.6) | 377 (9.4) | 82 (25.2) | <0.001 |
| Liver dysfunction | 750 (17.3) | 624 (15.5) | 126 (38.7) | <0.001 |
| Malignancy | 250 (5.8) | 224 (5.6) | 26 (8.0) | 0.074 |
| Diabetic ketoacidosis | 171 (3.9) | 140 (3.5) | 31 (9.5) | <0.001 |
| Pneumonia | 456 (10.5) | 390 (9.7) | 66 (20.2) | <0.001 |
| CNS infection | 206 (4.7) | 183 (4.6) | 23 (7.1) | 0.041 |
| Cardiac enzymes, U/L | ||||
| Creatine kinase | 143 (73–346) | 141 (73–332) | 174 (75–668) | 0.001 |
| Creatine kinase isoenzyme | 28 (19–43) | 27 (19–42) | 40 (21–91) | <0.001 |
| Aspartate aminotransferase | 39 (27–68) | 37 (26–63) | 82 (40–261) | <0.001 |
| Lactate dehydrogenase | 334 (256–497) | 326 (252–468) | 567 (356–1077) | <0.001 |
APTT, activated partial thromboplastin time; CNS, central nervous system; ICU, intensive care unit.