Table 2

Baseline characteristics of CWH registered in MoCHiV between January 1986 and December 2022

TotalZurichLausanneGenevaBaselBernSt. GallenTicino
CWH included in MoCHiV
28581475237371615
Total infected children
 Active patients16 (6%)9 (11%)5 (11%)0 (0%)0 (0%)0 (0%)0 (0%)2 (13%)
 Transition to SHCS113 (40%)29 (36%)17 (36%)21 (40%)18 (49%)18 (49%)8 (50%)2 (13%)
 Voluntary discontinuation15 (5%)6 (7%)2 (4%)4 (8%)2 (5%)1 (3%)0 (0%)0 (0%)
 Died*61 (21%)23 (28%)10 (21%)7 (13%)6 (16%)5 (14%)2 (12%)8 (53%)
 Lost to follow-up80 (28%)14 (17%)13 (28%)20 (38%)11 (30%)13 (35%)6 (38%)3 (20%)
Participation of mother in SHCS
 No participation187 (66%)56 (69%)32 (68%)31 (60%)27 (73%)23 (62%)6 (38%)12 (80%)
 Participation98 (34%)25 (31%)15 (32%)21 (40%)10 (27%)14 (38%)10 (62%)3 (20%)
Age of inclusion
 At birth75 (26%)20 (25%)11 (23%)15 (29%)12 (32%)4 (11%)4 (25%)9 (60%)
 Later210 (74%)61 (75%)36 (77%)37 (71%)25 (68%)33 (89%)12 (75%)6 (40%)
 Median age at inclusion if later (IQR)3.8 (1.2–8.2)2.5 (0.9–5.1)5.6 (2.1–10.6)5.9 (3.5–10.6)4 (0.9–10)3.4 (1.6–6.3)4.2 (1.2–6.3)2 (0.8–3)
Sex
 Female150 (53%)42 (52%)25 (53%)29 (56%)21 (57%)16 (43%)7 (44%)10 (67%)
 Male135 (47%)39 (48%)22 (47%)23 (44%)16 (43%)21 (57%)9 (56%)5 (33%)
Ethnicity
 White82 (29%)28 (35%)15 (32%)11 (21%)12 (32%)13 (35%)2 (12%)1 (7%)
 Black74 (26%)9 (11%)14 (30%)21 (40%)15 (41%)7 (19%)6 (38%)2 (13%)
 Hispano-American13 (5%)2 (2%)3 (6%)3 (6%)0 (0%)2 (5%)3 (19%)0 (0%)
 Asian8 (3%)2 (2%)0 (0%)2 (4%)1 (3%)2 (5%)1 (6%)0 (0%)
 Unknown108 (38%)40 (49%)15 (32%)15 (29%)9 (24%)13 (35%)4 (25%)12 (80%)
Source of HIV infection
 Vertical transmission217 (76%)59 (73%)37 (79%)47 (90%)24 (65%)29 (78%)12 (75%)9 (60%)
 Blood products4 (1%)1 (1%)2 (4%)1 (2%)0 (0%)0 (0%)0 (0%)0 (0%)
 Heterosexual contact1 (0%)0 (0%)0 (0%)0 (0%)1 (3%)0 (0%)0 (0%)0 (0%)
 Unknown63 (22%)21 (26%)8 (17%)4 (8%)12 (32%)8 (22%)4 (25%)6 (40%)
Median follow-up time in years
 Median (IQR)8.3 (2.0–15)7.9 (1.5–16)6.9 (2.2–12)9.2 (2.6–15)9.4 (3.1–16)11 (5.8–15)4.1 (0–13)1.3 (0–10)
  • *Cause of death overall: HIV (n=53), SIDS (n=2), others (n=6).

  • CWH, children with HIV; MoCHiV, Swiss Mother and Child HIV Cohort Study; SHCS, Swiss HIV Cohort Study; SIDS, sudden infant death syndrome.