Table 1

General characteristics of the included studies in the meta-analysis

StudyCountryStudy designNumber of eyesAge(years)OCTA deviceScan sizePregnancy period (weeks)NOS score
Yildirim et al18TurkeyCross-sectional studyPregnancy: 40
Controls: 40
Pregnancy: 28.80±5.27
Controls: 29.23±5.39
OptovueSCPVD, DCPVD: 6×6 mm
FAZ: 3×3 mm
34 (28–41)7
Hepokur et al19TurkeyProspective, cross-sectional studyPregnancy: 97 controls: 34Pregnancy: 30.32±6.34
Controls: 29.38±7.03
Optovue6×6 mm34.47±3.346
Pota and Apaydın20TurkeyCross-sectional studyPregnancy: 41
Controls: 45
Pregnancy: 30.8±5.9
Controls: 29.7±5.9
Topcon6×6 mm31±27
Chanwimol et al21USAProspective, case–control studyPregnancy: 19
Controls: 44
Pregnancy: 36±7
Controls: 35±8
Optovue3×3 mm33±37
Su et al22USAProspective, case–control studyPregnancy: 22
Controls: 23
Pregnancy: 32.27±6.96
Controls: 30.08±5.49
Heidelberg10°×10°33±3.597
  • DCP VD, deep capillary plexus vascular density; FAZ, foveal avascular zone; NOS, Newcastle-Ottawa Scale; OCTA, optical coherence tomography angiography; SCP VD, superficial capillary plexus VD.