General characteristics of the included studies in the meta-analysis
Study | Country | Study design | Number of eyes | Age(years) | OCTA device | Scan size | Pregnancy period (weeks) | NOS score |
Yildirim et al18 | Turkey | Cross-sectional study | Pregnancy: 40 Controls: 40 | Pregnancy: 28.80±5.27 Controls: 29.23±5.39 | Optovue | SCPVD, DCPVD: 6×6 mm FAZ: 3×3 mm | 34 (28–41) | 7 |
Hepokur et al19 | Turkey | Prospective, cross-sectional study | Pregnancy: 97 controls: 34 | Pregnancy: 30.32±6.34 Controls: 29.38±7.03 | Optovue | 6×6 mm | 34.47±3.34 | 6 |
Pota and Apaydın20 | Turkey | Cross-sectional study | Pregnancy: 41 Controls: 45 | Pregnancy: 30.8±5.9 Controls: 29.7±5.9 | Topcon | 6×6 mm | 31±2 | 7 |
Chanwimol et al21 | USA | Prospective, case–control study | Pregnancy: 19 Controls: 44 | Pregnancy: 36±7 Controls: 35±8 | Optovue | 3×3 mm | 33±3 | 7 |
Su et al22 | USA | Prospective, case–control study | Pregnancy: 22 Controls: 23 | Pregnancy: 32.27±6.96 Controls: 30.08±5.49 | Heidelberg | 10°×10° | 33±3.59 | 7 |
DCP VD, deep capillary plexus vascular density; FAZ, foveal avascular zone; NOS, Newcastle-Ottawa Scale; OCTA, optical coherence tomography angiography; SCP VD, superficial capillary plexus VD.