Measurements per follow-up points
| After initiating VS (T1) | Beginning of VS weaning (T2) | Data collection after weaning VS (T3) | After hospital discharge (T4) | |
| Demographic characteristics | X | |||
| Clinical characteristics | X | |||
| SOFA score | X | X | X | |
| Vital signs | X | X | X | |
| Cardiac output | X | X | X | |
| VS duration (hours) | X | X | X | |
| total NE administered (mg) | X | |||
| VS dose (cumulative dose) | X | X | X | |
| Fluids administered | X | X | X | |
| NE dose (mcg/kg/min) | X | X | X | |
| EaDyn | x | X | X | |
| MAP | X | X | X | |
| Lactate | X | X | X | |
| Diuresis | X | X | x | |
| Renal-related outcomes | X | X | X | X |
| ICU stay | X | |||
| Hospital stay | X | |||
| Mortality | X | |||
| Adverse events | X | X | X |
EaDyn, dynamic arterial elastance; ICU, intensive care unit; MAP, mean arterial pressure; NE, norepinephrine; SOFA, Sequential Organ Failure Assessment; VS, vasopressor support.