Table 2

Association between the CONUT score and mortality in patients with DKD

Variables	Model 1	P value	Model 2	P value
Variables	HR (95% CI)	P value	HR (95% CI)	P value
All-cause mortality
COUNT (continuous)	1.53 (1.37 to 1.71)	<0.001	1.30 (1.15 to 1.46)	<0.001
COUNT
0–1	Ref		Ref
2–4	1.68 (1.31 to 2.16)	<0.001	1.12 (0.91 to 1.37)	0.290
5–12	4.48 (2.41 to 8.36)	<0.001	2.80 (1.42 to 5.51)	0.003
CVD-related mortality
COUNT (continuous)	1.07 (0.93 to 1.23)	0.323	1.07 (0.92 to 1.24)	0.381
COUNT
0–1	Ref		Ref
2–4	0.95 (0.74 to 1.23)	0.723	0.94 (0.71 to 1.24)	0.656
5–12	1.82 (0.84 to 3.94)	0.131	1.67 (0.82 to 3.39)	0.159
Diabetes-related mortality
COUNT (continuous)	1.10 (0.99 to 1.21)	0.066	1.09 (0.98 to 1.22)	0.099
COUNT
0–1	Ref		Ref
2–4	1.01 (0.83 to 1.24)	0.904	1.00 (0.80 to 1.24)	0.995
5–12	1.90 (1.10 to 3.28)	0.022	1.78 (1.02 to 3.11)	0.041
Nephropathy-related mortality
COUNT (continuous)	1.10 (0.99 to 1.22)	0.076	1.13 (1.00 to 1.27)	0.051
COUNT
0–1	Ref		Ref
2–4	1.05 (0.84 to 1.31)	0.655	1.09 (0.85 to 1.38)	0.500
5–12	1.84 (1.07 to 3.17)	0.026	1.84 (1.04 to 3.24)	0.036
Other cause-related mortality
COUNT (continuous)	1.56 (1.35 to 1.80)	<0.001	1.54 (1.31 to 1.82)	<0.001
COUNT
0–1	Ref		Ref
2–4	1.60 (1.15 to 2.22)	0.005	1.24 (0.91 to 1.68)	0.167
5–12	5.54 (2.45 to 12.53)	<0.001	6.54 (3.18 to 13.45)	<0.001

Model 1, a univariate model; model 2, a multivariate model adjusted for age, race, marital status, smoking, hypertension, CVD, DR, PIR, antidiabetics, diuretics, UACR, uric acid, energy, protein, total fat, sodium and eGFR.
CONUT, Controlling Nutritional Status; CVD, cardiovascular disease; DKD, diabetic kidney disease; DR, diabetic retinopathy; eGFR, estimated glomerular filtration rate; PIR, poverty income ratio; UACR, urinary albumin to creatinine ratio.