OR (95% CI) for clinical LUTS across combined blood immune-inflammatory indexes*
| Crude model | P value | Model 1 | P value | Model 2 | P value | |
| SIRI+CRP (low SIRI<1.14, high SIRI≥1.14; low CRP<0.43, high CRP≥0.43) | ||||||
| Low SIRI and low CRP | 1 (Reference) | 1 (Reference) | 1 (Reference) | |||
| High SIRI and low CRP | 1.83 (1.34 to 2.50) | <0.01 | 1.60 (1.13 to 2.25) | 0.01 | 1.56 (1.10 to 2.21) | 0.02 |
| Low SIRI and high CRP | 2.28 (1.28 to 4.07) | 0.01 | 2.15 (1.12 to 4.14) | 0.02 | 2.10 (1.09 to 4.03) | 0.03 |
| High SIRI and high CRP | 2.90 (2.04 to 4.12) | <0.01 | 2.39 (1.65 to 3.48) | <0.01 | 2.26 (1.56 to 3.26) | <0.01 |
| NLR+CRP (low NLR<2.08, high NLR≥2.08) | ||||||
| Low NLR and low CRP | 1 (Reference) | 1 (Reference) | 1 (Reference) | |||
| High NLR and low CRP | 2.06 (1.54 to 2.77) | <0.01 | 1.82 (1.37 to 2.41) | <0.01 | 1.78 (1.33 to 2.38) | <0.01 |
| Low NLR and high CRP | 2.69 (1.57 to 4.62) | <0.01 | 2.40 (1.33 to 4.32) | 0.01 | 2.31 (1.29 to 4.14) | 0.01 |
| High NLR and high CRP | 3.07 (2.11 to 4.46) | <0.01 | 2.59 (1.73 to 3.86) | <0.01 | 2.44 (1.60 to 3.71) | <0.01 |
| dNLR+CRP (low dNLR<1.84, high dNLR≥1.84) | ||||||
| Low dNLR and low CRP | 1 (Reference) | 1 (Reference) | 1 (Reference) | |||
| High dNLR and low CRP | 2.03 (1.39 to 2.97) | <0.01 | 1.88 (1.24 to 2.84) | <0.01 | 1.87 (1.22 to 2.87) | 0.01 |
| Low dNLR and high CRP | 2.16 (1.37 to 3.41) | <0.01 | 2.01 (1.23 to 3.26) | 0.01 | 1.99 (1.23 to 3.23) | 0.01 |
| High dNLR and high CRP | 2.84 (1.66 to 4.87) | <0.01 | 2.38 (1.35 to4.21) | <0.01 | 2.16 (1.21 to 3.87) | 0.01 |
Model 1 was adjusted for age, race/ethnicity, education level, smoking status, alcohol use and BMI.
Model 2 was additionally adjusted for total cholesterol, and a history of diabetes and hypertension.
*Values are numerical values or weighted OR (95% CI).
BMI, body mass index; CRP, C reactive protein; dNLR, derived NLR; LUTS, lower urinary tract symptoms; NLR, neutrophil to lymphocyte ratio; SIRI, systemic inflammation response index.