Qualitative and mixed-methods data analysis to evaluate intervention
| RE-AIM | Data source | Analysis |
| Reach | Management data | Proportion and characteristics of practitioners and patients taking part. Reasons for declining. |
| Effectiveness | All-comers group | Apply analysis plan from main trial to test intervention effectiveness in all-comers group. |
| Qualitative data (patients and practitioners) | Compare experiences of EMPathicO across in-person, telephone and video consultations, and for musculoskeletal pain versus other conditions (framework analysis). | |
| Adoption | Management data | Proportion and characteristics of invited practices taking part. Reasons for declining. |
| Implementation | LifeGuide usage and qualitative data | Assess patterns of usage and ‘effective engagement’ with EMPathicO. Explore barriers and facilitators to implementation in practice, drawing on Normalisation Process Theory88 (framework analysis). |
| Maintenance | Qualitative data (patients and practitioners) | Explore opportunities to embed EMPathicO in existing training structures. Examine long-term maintenance of practitioner behaviour change and effects on patients (reflexive thematic analysis). |