Statistical power for various standardised effect sizes
iBV event rate | Sample size=150* | Rho | Statistical power | |||
With iBV | Normal microbiota | 80% | 85% | 90% | ||
10% | 15 | 75 | 0.2 | 0.38 | 0.41 | 0.44 |
10% | 15 | 75 | 0.3 | 0.45 | 0.48 | 0.52 |
10% | 15 | 75 | 0.4 | 0.51 | 0.55 | 0.60 |
14% | 21 | 69 | 0.2 | 0.33 | 0.36 | 0.39 |
14% | 21 | 69 | 0.3 | 0.40 | 0.43 | 0.46 |
14% | 21 | 69 | 0.4 | 0.45 | 0.49 | 0.52 |
18% | 27 | 63 | 0.2 | 0.31 | ![]() | 0.36 |
18% | 27 | 63 | 0.3 | 0.37 | 0.39 | 0.43 |
18% | 27 | 63 | 0.4 | 0.42 | 0.45 | 0.48 |
*We anticipate that the remaining participants will have an intermediate Nugent score of 4-6.
iBV, incident bacterial vaginosis.