Patient characteristics
Characteristics | Overall (n=726) | LAA thrombus* | P value | |
Positive (n=57) | Negative (n=669) | |||
Age, year | 61±11 | 64±10 | 61±11 | 0.129 |
Male | 437 (60.2) | 36 (63.2) | 401 (59.9) | 0.634 |
Paroxysmal AF | 436 (60.1) | 30 (52.6) | 406 (60.7) | 0.233 |
AF course, month | 42±83 | 39±45 | 43±85 | 0.540 |
CHA2DS2-VASc score | 2±2 | 3±2 | 2±2 | 0.089 |
Congestive heart failure | 116 (16.0) | 18 (31.6) | 98 (14.6) | 0.001 |
Hypertension | 346 (47.7) | 25 (43.9) | 321 (48.0) | 0.550 |
Diabetes mellitus | 107 (14.7) | 10 (17.5) | 97 (14.5) | 0.534 |
Previous stroke/TIA | 91 (12.5) | 14 (24.6) | 77 (11.5) | 0.004 |
Vascular disease | 292 (40.2) | 22 (38.6) | 270 (40.4) | 0.795 |
LAAPD, mm | 36±7 | 41±9 | 36±7 | <0.001 |
LVEDD, mm | 46±5 | 49±7 | 46±5 | 0.006 |
LVEF, % | 60±8 | 56±11 | 60±7 | 0.005 |
Complex LAA morphology | 289 (39.8) | 35 (61.4) | 254 (38.0) | 0.001 |
CCT results | ||||
Filling defects | 43 (5.9) | 39 (68.4) | 4 (0.6) | <0.001 |
No filling defects | 683 (94.1) | 18 (31.6) | 665 (99.4) |
Values are mean±SD or n (%).
*The thrombi were detected using the TEE.
AF, atrial fibrillation; CCT, cardiac CT; CHA2DS2-VASc, congestive heart failure, hypertension, age ≥75 years (doubled), diabetes, previous stroke/TIA/thromboembolism (doubled), vascular disease, age 65–74 years and sex category (female); LAA, left atrial appendage; LAAPD, left atrial anterior-posterior diameter; LVEDD, left ventricular end-diastolic diameter; LVEF, left ventricular ejection fraction; TEE, trans-oesophageal echocardiography; TIA, transient ischaemic attack.