List of predictors included in current risk tools for dementia, diabetes, myocardial infarction and stroke
| Risk factor category | Dementia risk tools (CAIDE, ANU ADRI, LIBRA) | Cardiovascular risk tools (Framingham Risk Tools- Hard Coronary Heart Disease, 10-year/30- year risk of CVD, CVD check) | Diabetes risk tools (AUSDRISK, Framingham risk score for diabetes) | Stroke risk tool (Framingham stroke risk score) |
| Demographic variables | ||||
| Age and sex | Y | Y | Y | Y |
| Education | Y | – | – | – |
| Ethnicity | – | Y | Y | – |
| Parental/family history of disease | – | Y | Y | – |
| Medical risk factors | ||||
| Hypertension/systolic BP | Y | Y | Y | Y |
| Use of antihypertensives | – | Y | Y | Y |
| High total cholesterol | Y | Y | – | – |
| HDL cholesterol | – | Y | Y | – |
| Obesity/waist circumference | Y | Y | Y | – |
| Diabetes | Y | Y | – | Y |
| Depression | Y | – | – | – |
| Traumatic brain injury | Y | – | – | – |
| High blood glucose levels | – | – | Y | – |
| Triglycerides | – | – | Y | – |
| Chronic kidney disease/renal dysfunction | Y | Y | – | – |
| Urine for microalbumin and protein | – | Y | – | – |
| Atrial fibrillation | – | Y | – | Y |
| Prior cardiovascular disease | Y | – | – | Y |
| Left ventricular hypertrophy | – | – | – | Y |
| Lifestyle and behavioural risk factors | ||||
| Smoking | Y | Y | Y | Y |
| Physical inactivity | Y | Y | Y | – |
| Diet (fish intake, consumption of vegetables and fruits) | Y | Y | Y | – |
| Alcohol consumption | Y | Y | – | – |
| Social engagement | Y | – | – | – |
| Cognitive engagement | Y | – | – | – |
| Environmental exposure | ||||
| Pesticide exposure | Y | – | – | – |
ANU-ADRI, Australian National University Alzheimer’s Disease Risk Index; AUSDRISK, Australian type 2 Diabetes Risk Assessment tool; BP, blood pressure; CAIDE, Cardiovascular Risk Factors, Aging, and Incidence of Dementia; CVD, cardiovascular disease; LIBRA, LIfestyle and BRAin Health.