Table 2

Univariate and multivariable Cox regression analyses of cancer-specific survival

Variable	Univariate analysis		Multivariate analysis
Variable	HR	P value	HR	P value
Race
White	1 (ref)		1 (ref)
Black	1.88 (1.6 to 2.21)	<0.001	1.49 (1.26 to 1.75)	<0.001
Other*	1.03 (0.89 to 1.2)	0.697	1.15 (0.99 to 1.34)	0.072
Chemotherapy
No	1 (ref)		1 (ref)
Yes	1 (0.9 to 1.1)	0.958	0.84 (0.75 to 0.93)	0.001
Historical stage†
Localised	1 (ref)		1 (ref)
Regional	0.41 (0.17 to 0.98)	0.044	0.32 (0.13 to 0.78)	0.012
Distant	0.84 (0.35 to 2.03)	0.705	0.34 (0.14 to 0.82)	0.016
Tumour grade‡
I	1 (ref)		1 (ref)
II	1.51 (1.28 to 1.78)	<0.001	1.43 (1.21 to 1.68)	<0.001
III–IV	3.63 (3.12 to 4.23)	<0.001	2.79 (2.39 to 3.26)	<0.001
Radiation
No	1 (ref)		1 (ref)
Yes	0.67 (0.61 to 0.74)	<0.001	0.76 (0.69 to 0.84)	<0.001
FIGO stage
III	1 (ref)		1 (ref)
IV	3.33 (2.98 to 3.72)	<0.001	2.6 (2.26 to 3)	<0.001
Age at diagnosis (years)
24–64	1 (ref)		1 (ref)
65–75	1.47 (1.32 to 1.65)	<0.001	1.52 (1.36 to 1.7)	<0.001
76–96	2.37 (2.08 to 2.7)	<0.001	2.38 (2.08 to 2.73)	<0.001
Tumour size (mm)
0–35	1 (ref)		1 (ref)
36–78	1.54 (1.36 to 1.74)	<0.001	1.25 (1.1 to 1.41)	<0.001
79–790	2.38 (2.07 to 2.74)	<0.001	1.72 (1.48 to 2)	<0.001
Regional nodes positive
Negative	1 (ref)		1 (ref)
1–2	1.34 (1.2 to 1.5)	<0.001	1.36 (1.21 to 1.53)	<0.001
3–82	1.98 (1.76 to 2.24)	<0.001	1.86 (1.62 to 2.14)	<0.001
Income
≤$54 999	1 (ref)		1 (ref)
$55 000–69 999	0.82 (0.72 to 0.94)	0.003	0.82 (0.72 to 0.94)	0.003
≥$70 000	0.72 (0.63 to 0.82)	<0.001	0.75 (0.65 to 0.85)	<0.001

*American Indian/AK Native, Asian/Pacific Islander.
†Historical stage derived from Collaborative Stage for 2004–2015. Localised, an invasive neoplasm confined entirely to the organ of origin. Regional, a neoplasm that has extended. Distant, a neoplasm that has spread to parts of the body remote from the primary tumour.
‡I, well differentiated; II, moderately differentiated; III, poorly differentiated; IV, undifferentiated.
AK, Alaska; FIGO, International Federation of Gynecology and Obstetrics.