Pregnancy outcomes for the SHAPES cohort
| Outcomes | Definition |
| Maternal outcomes | |
| Gestational diabetes* | Fasting plasma glucose level of ≥5.6 mmol/L or 2 hour plasma glucose level of ≥7.8 mmol/L |
| Gestational hypertension | Blood pressure≥140/90 mm Hg on two occasions at least 4 hours apart after 20 weeks’ gestation |
| Pre-eclampsia | New onset of hypertension (>140 mm Hg systolic or >90 mm Hg diastolic) after 20 weeks of pregnancy with a new onset of proteinuria or/and maternal organ dysfunction or/and uteroplacental dysfunction. Early onset defined as onset of pre-eclampsia before 34 weeks gestation |
| Induction of labour | Non-surgical treatment to induce the labour |
| Caesarean section | Surgical delivery of baby (emergency or elective) |
| Instrumental delivery | Assisted birth when forceps or a ventouse suction cup is applied |
| Retained placenta | As reported in medical records |
| Maternal infection | As reported in medical records |
| Postpartum haemorrhage (PPH) | Third stage of labour and immediate postpartum period, measured in mL blood loss |
| Maternal length of stay in hospital | From admission date for any stay resulting in delivery to date of discharge |
| Infant outcomes | |
| Fetal growth | Measured at second and third trimester scans, including: Second trimester scan: fetal head circumference; fetal abdominal circumference; fetal femur length; estimated fetal weight Hadlock Third trimester scan: abdominal circumference; femur length; estimated fetal weight Hadlock; umbilical artery PI; end diastolic flow; Amniotic Fluid Index |
| Preterm birth | Birth before 37 weeks gestation |
| Late-term birth | Pregnancy that extends over 41 weeks gestation |
| Large for gestational age | Birth weight above the 90th centile for gestational age and sex on INTERGROWTH chart |
| Small for gestational age | Birth weight below the 10th centile for gestational age and sex on INTERGROWTH chart46 |
| Apgar score | 1 and 5 minutes |
| Neonatal jaundice | As reported in medical records |
| Neonatal respiratory distress (requiring resuscitation) | Any of the following: cords visualised meconium seen; cord visualised no meconium; facial air; facial oxygen; mucus extraction or suction; positive pressure by bag or mask; positive pressure by endotracheal tube |
| Feeding method | First feed: artificial; breast mother; breast donor; breast and artificial; no feed given Feed method at discharge: breastfeeding or artificial feed or both breast and artificial |
| Infant admission to specialist care | Admission to neonatal special care baby unit or intensive care unit, high-dependency care, transitional care; length of stay if admitted |
*Note this outcome can only be determined for those women who have had an oral glucose tolerance test.
SHAPES, Study of How Adiposity in Pregnancy has an Effect on outcomeS.