Cox regression analysis of acute cardiac drug therapy (CDT) (N=5770)
Acute CDT | ||||
Antihypertensive monotherapies | Crude HR (95%confidence interval) | P value | IPW adjusted* HR (95%confidence interval) | P value |
Reference:BBs | ||||
Exposure | ||||
ACEIs | 1.44 (1.35 to 1.55) | <0.001 | 1.06 (0.98 to 1.14) | 0.158 |
ARBs | 1.27 (1.15 to 1.40) | <0.001 | 0.99 (0.89 to 1.11) | 0.920 |
CCBs | 1.48 (1.34 to 1.63) | <0.001 | 1.26 (1.13 to 1.41) | < 0.001 |
Thiazides | 1.26 (1.18 to 1.35) | <0.001 | 0.88 (0.82 to 0.96) | 0.002 |
*IPW adjusted between antihypertensive monotherapies and gender, age, drugs for diabetes, drugs for RA, drugs for asthma/COPD, calendar-year periods.
ACEIs, ACE inhibitors ; ARBs, angiotensin II receptor blockers ; BBs, beta-blockers; CCBs, calcium channel blockers; COPD, chronic obstructive pulmonary disease; IPW, inverse probability weighting; RA, rheumatoid arthritis.