Table 3

Cox regression analysis of acute cardiac drug therapy (CDT) (N=5770)

Acute CDT
Antihypertensive monotherapiesCrude HR (95%confidence interval)P valueIPW adjusted* HR (95%confidence interval)P value
Reference:BBs
Exposure
ACEIs1.44 (1.35 to 1.55)<0.0011.06 (0.98 to 1.14)0.158
ARBs1.27 (1.15 to 1.40)<0.0010.99 (0.89 to 1.11)0.920
CCBs1.48 (1.34 to 1.63)<0.0011.26 (1.13 to 1.41)< 0.001
Thiazides1.26 (1.18 to 1.35)<0.0010.88 (0.82 to 0.96)0.002
  • *IPW adjusted between antihypertensive monotherapies and gender, age, drugs for diabetes, drugs for RA, drugs for asthma/COPD, calendar-year periods.

  • ACEIs, ACE inhibitors ; ARBs, angiotensin II receptor blockers ; BBs, beta-blockers; CCBs, calcium channel blockers; COPD, chronic obstructive pulmonary disease; IPW, inverse probability weighting; RA, rheumatoid arthritis.