Patients undergoing invasive mechanical ventilation in hospital

Any setting in hospital including intensive care unit, operating room, emergency department)

Paediatric and neonatal population

Non-invasive ventilation

Single lung ventilation

Animal studies (with no human component)

Study evaluates a method of setting optimal PEEP

Study reports an outcome (could be clinical or physiologic) associated with the setting of the PEEP by a specific method

Studies that arbitrarily set PEEP at a certain value (ie, 5 cmH₂O)

Any geographical location

Any duration of ventilation

None

Primary research studies (including randomised controlled trials, cohort studies, cross-sectional studies, case series)

Published abstracts will be included

None